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Gene: Egfr (epidermal growth factor receptor) Mus musculus
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Symbol: Egfr
Name: epidermal growth factor receptor
Description: Exhibits epidermal growth factor binding activity and epidermal growth factor-activated receptor activity. Predicted to contribute to nitric-oxide synthase regulator activity. Involved in several processes, including animal organ development; positive regulation of cell population proliferation; and protein autophosphorylation. Localizes to several cellular components, including the basolateral plasma membrane; endocytic vesicle; and perinuclear region of cytoplasm. Used to study aortic valve disease. Human ortholog(s) of this gene implicated in several diseases, including breast carcinoma; colorectal cancer; lung cancer (multiple); pancreatic cancer; and prostate cancer. Is expressed in several structures, including alimentary system; brain; integumental system; limb; and respiratory system. Orthologous to human EGFR (epidermal growth factor receptor); PARTICIPATES IN altered epidermal growth factor/neuregulin signaling pathway; cetuximab pharmacodynamics pathway; E-cadherin signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1,2,3,4,7,8-Hexachlorodibenzofuran; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; Erbb; Errb1; Errp; wa-2; wa2; Wa5; waved 2
Orthologs:
Homo sapiens (human) : EGFR (epidermal growth factor receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Egfr (epidermal growth factor receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Egfr (epidermal growth factor receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : EGFR (epidermal growth factor receptor)
Canis lupus familiaris (dog) : EGFR (epidermal growth factor receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Egfr (epidermal growth factor receptor)
Sus scrofa (pig) : EGFR (epidermal growth factor receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1116,752,203 - 16,918,158 (+)Ensembl
GRCm381116,752,203 - 16,913,907 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371116,652,206 - 16,813,910 (+)NCBIGRCm37mm9NCBIm37
MGSCv361116,652,206 - 16,813,909 (+)NCBImm8
Celera1117,126,474 - 17,287,898 (+)NCBICelera
Cytogenetic Map11 A2NCBI
cM Map119.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations