Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ets1 (E26 avian leukemia oncogene 1, 5' domain) Mus musculus
Analyze
Symbol: Ets1
Name: E26 avian leukemia oncogene 1, 5' domain
Description: Exhibits DNA-binding transcription factor activity and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of inflammatory response and positive regulation of transcription by RNA polymerase II. Localizes to the nucleus and transcription factor complex. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human ETS1 (ETS proto-oncogene 1, transcription factor); PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI196000; AI448617; avian erythroblastosis virus E26 oncogene 1; C-ets-1 protein (p54); D230050P06; Ets-1; MGC130355; MGC18571; p54; protein C-ets-1; Tpl1; tumor progression locus 1; vs
Orthologs:
Homo sapiens (human) : ETS1 (ETS proto-oncogene 1, transcription factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ets1 (ETS proto-oncogene 1, transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ets1 (ETS proto-oncogene 1, transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : ETS1 (ETS proto-oncogene 1, transcription factor)
Canis lupus familiaris (dog) : ETS1 (ETS proto-oncogene 1, transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ets1 (ETS proto-oncogene 1, transcription factor)
Sus scrofa (pig) : ETS1 (ETS proto-oncogene 1, transcription factor)
Chlorocebus sabaeus (African green monkey) : ETS1 (ETS proto-oncogene 1, transcription factor)
Heterocephalus glaber (naked mole-rat) : Ets1 (ETS proto-oncogene 1, transcription factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl932,636,221 - 32,757,820 (+)EnsemblGRCm38mm10GRCm38
GRCm38932,636,183 - 32,757,820 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37932,503,627 - 32,565,405 (+)NCBIGRCm37mm9NCBIm37
MGSCv36932,445,607 - 32,507,385 (+)NCBImm8
Celera929,958,312 - 30,019,948 (+)NCBICelera
Cytogenetic Map9A4NCBI
cM Map917.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ets1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10554
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.