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Gene: Fgfr2 (fibroblast growth factor receptor 2) Mus musculus
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Symbol: Fgfr2
Name: fibroblast growth factor receptor 2
CRRD ID: 10581
Description: Exhibits fibroblast growth factor binding activity. Involved in several processes, including animal organ development; positive regulation of cell population proliferation; and regulation of signal transduction. Localizes to excitatory synapse and nucleus. Predicted to colocalize with collagen-containing extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study Beare-Stevenson cutis gyrata syndrome; Crouzon syndrome; Pfeiffer syndrome; acrocephalosyndactylia; and intestinal atresia. Human ortholog(s) of this gene implicated in several diseases, including Antley-Bixler syndrome; Beare-Stevenson cutis gyrata syndrome; Jackson-Weiss syndrome; reproductive organ cancer (multiple); and synostosis (multiple). Orthologous to human FGFR2 (fibroblast growth factor receptor 2); PARTICIPATES IN fibroblast growth factor signaling pathway; endocytosis pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU043015; AW556123; Bek; Fgfr; Fgfr-; Fgfr-2; Fgfr-7; Fgfr2b; Fgfr7; keratinocyte growth factor receptor; KGFR; KGFRTr; MGC102519; svs
Orthologs:
Homo sapiens (human) : FGFR2 (fibroblast growth factor receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fgfr2 (fibroblast growth factor receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgfr2 (fibroblast growth factor receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FGFR2 (fibroblast growth factor receptor 2)
Canis lupus familiaris (dog) : FGFR2 (fibroblast growth factor receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgfr2 (fibroblast growth factor receptor 2)
Sus scrofa (pig) : FGFR2 (fibroblast growth factor receptor 2)
Chlorocebus sabaeus (African green monkey) : FGFR2 (fibroblast growth factor receptor 2)
Heterocephalus glaber (naked mole-rat) : Fgfr2 (fibroblast growth factor receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397129,764,181 - 129,868,538 (-)NCBI
GRCm387130,162,451 - 130,266,808 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7130,162,451 - 133,123,350 (-)EnsemblGRCm38mm10GRCm38
MGSCv377137,305,965 - 137,410,322 (-)NCBIGRCm37mm9NCBIm37
MGSCv367129,954,867 - 130,057,411 (-)NCBImm8
Celera7129,989,855 - 130,093,942 (-)NCBICelera
Cytogenetic Map7F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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