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Gene: Fhl1 (four and a half LIM domains 1) Mus musculus
Symbol: Fhl1
Name: four and a half LIM domains 1
Description: Predicted to have ion channel binding activity. Predicted to be involved in several processes, including negative regulation of mitotic cell cycle phase transition; regulation of membrane depolarization; and regulation of potassium ion transport. Predicted to localize to cytosol; nucleus; and plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Used to study scapuloperoneal myopathy. Human ortholog(s) of this gene implicated in X-linked Emery-Dreifuss muscular dystrophy 6; reducing body myopathy 1A; and reducing body myopathy 1B. Orthologous to human FHL1 (four and a half LIM domains 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FHL-1; four and a half LIM domains protein 1; KyoT; RAM14-1; RBP-associated molecule 14-1; skeletal muscle LIM-protein 1; SLIM; SLIM-1
Homo sapiens (human) : FHL1 (four and a half LIM domains 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fhl1 (four and a half LIM domains 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fhl1 (four and a half LIM domains 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FHL1 (four and a half LIM domains 1)
Canis lupus familiaris (dog) : FHL1 (four and a half LIM domains 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fhl1 (four and a half LIM domains 1)
Sus scrofa (pig) : FHL1 (four and a half LIM domains 1)
Chlorocebus sabaeus (African green monkey) : FHL1 (four and a half LIM domains 1)
Heterocephalus glaber (naked mole-rat) : Fhl1 (four and a half LIM domains 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 EnsemblX56,731,787 - 56,793,346 (+)EnsemblGRCm38mm10GRCm38
GRCm38X56,731,209 - 56,793,346 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X53,984,964 - 54,046,523 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X53,078,598 - 53,140,127 (+)NCBImm8
CeleraX43,224,152 - 43,274,965 (+)NCBICelera
Cytogenetic MapXA6NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fhl1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10588
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.