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Gene: Fhl1 (four and a half LIM domains 1) Mus musculus
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Symbol: Fhl1
Name: four and a half LIM domains 1
Description: Predicted to have ion channel binding activity. Predicted to be involved in several processes, including negative regulation of mitotic cell cycle phase transition; regulation of membrane depolarization; and regulation of potassium ion transport. Predicted to localize to cytosol; nucleus; and plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Used to study scapuloperoneal myopathy. Human ortholog(s) of this gene implicated in X-linked Emery-Dreifuss muscular dystrophy 6; reducing body myopathy 1A; and reducing body myopathy 1B. Orthologous to human FHL1 (four and a half LIM domains 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FHL-1; four and a half LIM domains protein 1; KyoT; RAM14-1; RBP-associated molecule 14-1; skeletal muscle LIM-protein 1; SLIM; SLIM-1
Orthologs:
Homo sapiens (human) : FHL1 (four and a half LIM domains 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fhl1 (four and a half LIM domains 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fhl1 (four and a half LIM domains 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FHL1 (four and a half LIM domains 1)
Canis lupus familiaris (dog) : FHL1 (four and a half LIM domains 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fhl1 (four and a half LIM domains 1)
Sus scrofa (pig) : FHL1 (four and a half LIM domains 1)
Chlorocebus sabaeus (African green monkey) : FHL1 (four and a half LIM domains 1)
Heterocephalus glaber (naked mole-rat) : Fhl1 (four and a half LIM domains 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 EnsemblX56,731,787 - 56,793,346 (+)EnsemblGRCm38mm10GRCm38
GRCm38X56,731,209 - 56,793,346 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X53,984,964 - 54,046,523 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X53,078,598 - 53,140,127 (+)NCBImm8
CeleraX43,224,152 - 43,274,965 (+)NCBICelera
Cytogenetic MapXA6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fhl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10588
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.