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Gene: Gad2 (glutamic acid decarboxylase 2) Mus musculus
Symbol: Gad2
Name: glutamic acid decarboxylase 2
Description: Predicted to have glutamate binding activity; glutamate decarboxylase activity; and pyridoxal phosphate binding activity. Predicted to be involved in glutamate decarboxylation to succinate. Localizes to axon; cytoplasm; and synapse. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Used to study epilepsy and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in gestational diabetes; schizophrenia; and type 1 diabetes mellitus. Orthologous to human GAD2 (glutamate decarboxylase 2); PARTICIPATES IN alanine, aspartate and glutamate metabolic pathway; beta-alanine metabolic pathway; butanoate metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6330404F12Rik; 65 kDa glutamic acid decarboxylase; GAD(65); Gad-2; GAD-65; GAD65; glutamate decarboxylase 2; glutamate decarboxylase 65 kDa isoform
Homo sapiens (human) : GAD2 (glutamate decarboxylase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gad2 (glutamate decarboxylase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gad2 (glutamate decarboxylase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GAD2 (glutamate decarboxylase 2)
Canis lupus familiaris (dog) : GAD2 (glutamate decarboxylase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gad2 (glutamate decarboxylase 2)
Sus scrofa (pig) : GAD2 (glutamate decarboxylase 2)
Chlorocebus sabaeus (African green monkey) : GAD2 (glutamate decarboxylase 2)
Heterocephalus glaber (naked mole-rat) : Gad2 (glutamate decarboxylase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl222,622,205 - 22,693,874 (+)EnsemblGRCm38mm10GRCm38
GRCm38222,621,015 - 22,693,877 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37222,477,847 - 22,549,397 (+)NCBIGRCm37mm9NCBIm37
MGSCv36222,473,967 - 22,542,641 (+)NCBImm8
Celera222,352,193 - 22,424,544 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map215.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gad2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10616
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.