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Gene: Ghr (growth hormone receptor) Mus musculus
Symbol: Ghr
Name: growth hormone receptor
Description: Exhibits growth hormone receptor activity and peptide hormone binding activity. Involved in several processes, including growth hormone receptor signaling pathway; positive regulation of peptidyl-tyrosine phosphorylation; and taurine metabolic process. Localizes to the extrinsic component of membrane; nucleus; and plasma membrane. Used to study Laron syndrome. Human ortholog(s) of this gene implicated in several diseases, including Laron syndrome; familial hypercholesterolemia; isolated growth hormone deficiency; osteoarthritis; and type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and integumental system. Orthologous to human GHR (growth hormone receptor); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA986417; GH receptor; GHBP; GHR/BP; Growth hormone receptor precursor (GH receptor) (GH binding protein) (GHBP) (Serum binding protein); growth hormone receptor/binding protein; growth hormone receptor/binding protein, high molecular weight; growth hormone receptor/binding protein, low molecular weight; somatotropin receptor
Homo sapiens (human) : GHR (growth hormone receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ghr (growth hormone receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ghr (growth hormone receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : GHR (growth hormone receptor)
Canis lupus familiaris (dog) : GHR (growth hormone receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ghr (growth hormone receptor)
Sus scrofa (pig) : GHR (growth hormone receptor)
Chlorocebus sabaeus (green monkey) : GHR (growth hormone receptor)
Heterocephalus glaber (naked mole-rat) : Ghr (growth hormone receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl153,317,760 - 3,583,492 (-)Ensembl
GRCm38153,317,755 - 3,583,352 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37153,267,760 - 3,533,230 (-)NCBIGRCm37mm9NCBIm37
MGSCv36153,267,774 - 3,533,231 (-)NCBImm8
Celera153,182,316 - 3,449,004 (-)NCBICelera
Cytogenetic Map15 A1NCBI
cM Map151.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ghr
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10644
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.