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Gene: Gnmt (glycine N-methyltransferase) Mus musculus
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Symbol: Gnmt
Name: glycine N-methyltransferase
Description: Exhibits glycine N-methyltransferase activity and glycine binding activity. Involved in several processes, including glycogen metabolic process; protein homotetramerization; and regulation of gluconeogenesis. Predicted to localize to the cytosol. Used to study glycine N-methyltransferase deficiency and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in glycine N-methyltransferase deficiency. Is expressed in several structures, including integumental system; limb; nose; pancreas tip epithelium; and skeleton. Orthologous to human GNMT (glycine N-methyltransferase); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; methionine cycle/metabolic pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glycine N methyl transferase
Orthologs:
Homo sapiens (human) : GNMT (glycine N-methyltransferase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gnmt (glycine N-methyltransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnmt (glycine N-methyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : GNMT (glycine N-methyltransferase)
Canis lupus familiaris (dog) : GNMT (glycine N-methyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101964621 (glycine N-methyltransferase)
Sus scrofa (pig) : GNMT (glycine N-methyltransferase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1746,725,664 - 46,729,168 (-)Ensembl
GRCm381746,725,664 - 46,729,211 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371746,862,613 - 46,866,114 (-)NCBIGRCm37mm9NCBIm37
MGSCv361746,188,855 - 46,192,356 (-)NCBImm8
Celera1750,161,350 - 50,164,841 (-)NCBICelera
Cytogenetic Map17 CNCBI
cM Map1722.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gnmt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10671
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.