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Gene: Grin2a (glutamate receptor, ionotropic, NMDA2A (epsilon 1)) Mus musculus
Symbol: Grin2a
Name: glutamate receptor, ionotropic, NMDA2A (epsilon 1)
Description: Exhibits NMDA glutamate receptor activity and calcium channel activity. Predicted to contribute to extracellularly glutamate-gated ion channel activity and ionotropic glutamate receptor activity. Involved in several processes, including learning or memory; long-term synaptic potentiation; and response to amphetamine. Localizes to several cellular components, including NMDA selective glutamate receptor complex; glutamatergic synapse; and synaptic membrane. Is expressed in several structures, including central nervous system; eye; hindlimb phalanx; intestine; and limb mesenchyme. Human ortholog(s) of this gene implicated in Huntington's disease; bipolar disorder; and schizophrenia. Orthologous to human GRIN2A (glutamate ionotropic receptor NMDA type subunit 2A); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GluN2A; GluRepsilon1; glutamate [NMDA] receptor subunit epsilon-1; glutamate receptor ionotropic, NMDA 2A; N-methyl D-aspartate receptor subtype 2A; NMDAR2A; NR2A
Related Pseudogenes: Gm7328  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl169,567,898 - 9,995,560 (-)EnsemblGRCm38mm10GRCm38
GRCm38169,567,901 - 9,996,083 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37169,577,803 - 9,992,626 (-)NCBIGRCm37mm9NCBIm37
MGSCv36169,491,265 - 9,906,111 (-)NCBImm8
Celera1610,217,398 - 10,625,063 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map165.28NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Grin2a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10686
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.