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Gene: Hmox1 (heme oxygenase 1) Mus musculus
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Symbol: Hmox1
Name: heme oxygenase 1
Description: Predicted to have several functions, including heme binding activity; heme oxygenase (decyclizing) activity; and protein homodimerization activity. Involved in several processes, including cellular response to cisplatin; cellular response to metal ion; and regulation of macroautophagy. Localizes to the nucleus. Used to study hemochromatosis and malaria. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebrovascular disease (multiple); factor VIII deficiency; lung disease (multiple); and sickle cell anemia. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Orthologous to human HMOX1 (heme oxygenase 1); PARTICIPATES IN acute intermittent porphyria pathway; erythropoietic porphyria pathway; heme degradation pathway; INTERACTS WITH (+)-alpha-viniferin; (+)-pilocarpine; (+)-taxifolin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D8Wsu38e; heme oxygenase (decycling) 1; Hemox; hemoxygenase; Hmox; HO-1; HO1; Hsp32; P32 protein
Orthologs:
Homo sapiens (human) : HMOX1 (heme oxygenase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hmox1 (heme oxygenase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hmox1 (heme oxygenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HMOX1 (heme oxygenase 1)
Canis lupus familiaris (dog) : HMOX1 (heme oxygenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hmox1 (heme oxygenase 1)
Sus scrofa (pig) : HMOX1 (heme oxygenase 1)
Chlorocebus sabaeus (green monkey) : HMOX1 (heme oxygenase 1)
Heterocephalus glaber (naked mole-rat) : Hmox1 (heme oxygenase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl875,093,621 - 75,100,589 (+)Ensembl
GRCm38875,093,618 - 75,100,593 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37877,617,517 - 77,624,492 (+)NCBIGRCm37mm9NCBIm37
MGSCv36877,989,694 - 77,996,657 (+)NCBImm8
Celera879,400,848 - 79,407,824 (+)NCBICelera
Cytogenetic Map8C1NCBI
cM Map835.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model