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Gene: Foxa2 (forkhead box A2) Mus musculus
Symbol: Foxa2
Name: forkhead box A2
CRRD ID: 10719
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including anterior/posterior axis specification; nervous system development; and regulation of transcription, DNA-templated. Localizes to nucleus and transcription regulator complex. Is expressed in several structures, including central nervous system; endoderm; genitourinary system; gut; and respiratory system. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FOXA2 (forkhead box A2); PARTICIPATES IN forkhead class A signaling pathway; Hedgehog signaling pathway; maturity-onset diabetes of the young pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17beta-hydroxy-5alpha-androstan-3-one.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: forkhead box protein A2; hepatocyte nuclear factor 3 beta (winged helix transcription factor); hepatocyte nuclear factor 3-beta; hepatocyte nuclear factor-3 beta; Hnf-3; HNF-3-beta; Hnf-3b; Hnf3; HNF3-be; HNF3-beta; Hnf3b; HNF3be; HNF3beta; Tcf-3b; Tcf3b
Homo sapiens (human) : FOXA2 (forkhead box A2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Foxa2 (forkhead box A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxa2 (forkhead box A2)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXA2 (forkhead box A2)
Canis lupus familiaris (dog) : FOXA2 (forkhead box A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxa2 (forkhead box A2)
Sus scrofa (pig) : FOXA2 (forkhead box A2)
Chlorocebus sabaeus (African green monkey) : FOXA2 (forkhead box A2)
Heterocephalus glaber (naked mole-rat) : Foxa2 (forkhead box A2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm392147,884,797 - 147,888,889 (-)NCBI
GRCm382148,042,877 - 148,046,969 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2148,042,877 - 148,046,969 (-)EnsemblGRCm38mm10GRCm38
MGSCv372147,868,614 - 147,872,705 (-)NCBIGRCm37mm9NCBIm37
MGSCv362147,734,364 - 147,738,410 (-)NCBImm8
Celera2149,306,403 - 149,310,523 (-)NCBICelera
Cytogenetic Map2G3NCBI
cM Map273.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Foxa2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10719
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.