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Gene: Foxa2 (forkhead box A2) Mus musculus
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Symbol: Foxa2
Name: forkhead box A2
CRRD ID: 10719
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including anterior/posterior axis specification; nervous system development; and regulation of transcription, DNA-templated. Localizes to nucleus and transcription regulator complex. Is expressed in several structures, including central nervous system; endoderm; genitourinary system; gut; and respiratory system. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FOXA2 (forkhead box A2); PARTICIPATES IN forkhead class A signaling pathway; Hedgehog signaling pathway; maturity-onset diabetes of the young pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17beta-hydroxy-5alpha-androstan-3-one.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: forkhead box protein A2; hepatocyte nuclear factor 3 beta (winged helix transcription factor); hepatocyte nuclear factor 3-beta; hepatocyte nuclear factor-3 beta; Hnf-3; HNF-3-beta; Hnf-3b; Hnf3; HNF3-be; HNF3-beta; Hnf3b; HNF3be; HNF3beta; Tcf-3b; Tcf3b
Orthologs:
Homo sapiens (human) : FOXA2 (forkhead box A2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Foxa2 (forkhead box A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxa2 (forkhead box A2)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXA2 (forkhead box A2)
Canis lupus familiaris (dog) : FOXA2 (forkhead box A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxa2 (forkhead box A2)
Sus scrofa (pig) : FOXA2 (forkhead box A2)
Chlorocebus sabaeus (African green monkey) : FOXA2 (forkhead box A2)
Heterocephalus glaber (naked mole-rat) : Foxa2 (forkhead box A2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392147,884,797 - 147,888,889 (-)NCBI
GRCm382148,042,877 - 148,046,969 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2148,042,877 - 148,046,969 (-)EnsemblGRCm38mm10GRCm38
MGSCv372147,868,614 - 147,872,705 (-)NCBIGRCm37mm9NCBIm37
MGSCv362147,734,364 - 147,738,410 (-)NCBImm8
Celera2149,306,403 - 149,310,523 (-)NCBICelera
Cytogenetic Map2G3NCBI
cM Map273.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Foxa2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10719
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.