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Gene: Onecut1 (one cut domain, family member 1) Mus musculus
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Symbol: Onecut1
Name: one cut domain, family member 1
CRRD ID: 10721
Description: Exhibits DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including Notch signaling pathway; animal organ development; and negative regulation of transforming growth factor beta receptor signaling pathway. Localizes to nucleus. Is expressed in several structures, including central nervous system; gut; liver and biliary system; retina; and urinary system. Orthologous to human ONECUT1 (one cut homeobox 1); PARTICIPATES IN maturity-onset diabetes of the young pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: D9Ertd423; D9Ertd423e; hepatic nuclear factor 6; hepatocyte nuclear factor 6; Hfh12; HNF; HNF-3/forkhead homolog 12; HNF-6; Hnf6; Hnf6b; Oc; OC-; OC-1; Oc1; one cut domain family member 1; one cut homeobox 1
Orthologs:
Homo sapiens (human) : ONECUT1 (one cut homeobox 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Onecut1 (one cut homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Onecut1 (one cut homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ONECUT1 (one cut homeobox 1)
Canis lupus familiaris (dog) : ONECUT1 (one cut homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Onecut1 (one cut homeobox 1)
Sus scrofa (pig) : ONECUT1 (one cut homeobox 1)
Chlorocebus sabaeus (African green monkey) : ONECUT1 (one cut homeobox 1)
Heterocephalus glaber (naked mole-rat) : Onecut1 (one cut homeobox 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39974,769,203 - 74,796,930 (+)NCBI
GRCm38974,861,921 - 74,889,648 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl974,861,921 - 74,891,781 (+)EnsemblGRCm38mm10GRCm38
MGSCv37974,709,728 - 74,737,455 (+)NCBIGRCm37mm9NCBIm37
MGSCv36974,648,524 - 74,676,252 (+)NCBImm8
Celera972,045,890 - 72,046,250 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map941.93NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Onecut1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10721
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.