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Gene: Hspa1l (heat shock protein 1-like) Mus musculus
Symbol: Hspa1l
Name: heat shock protein 1-like
CRRD ID: 10741
Description: Predicted to have several functions, including ATP binding activity; misfolded protein binding activity; and protein folding chaperone. Involved in binding activity of sperm to zona pellucida. Localizes to cell body and zona pellucida receptor complex. Predicted to colocalize with COP9 signalosome. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and limb segment. Human ortholog(s) of this gene implicated in Kawasaki disease; major depressive disorder; schizophrenia; systemic lupus erythematosus; and uveitis. Orthologous to human HSPA1L (heat shock protein family A (Hsp70) member 1 like); PARTICIPATES IN antigen processing and presentation pathway; endocytosis pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 70kD; heat shock 70 kDa protein 1-like; heat shock 70 kDa protein 1L; heat shock 70 kDa-like protein 1; heat shock 70kDa protein 1-like; heat shock protein cognate 70, testis; heat shock-related protein hsc70t; Hsc70; Hsc70t; inducible heat shock protein 70; MGC150263; MGC150264; Msh; Msh5; spermatid-specific heat shock protein 70
Related Pseudogenes: Gm8107  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391735,191,679 - 35,198,204 (+)NCBI
GRCm381734,972,703 - 34,979,228 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,972,703 - 34,979,285 (+)EnsemblGRCm38mm10GRCm38
MGSCv371735,109,648 - 35,116,173 (+)NCBIGRCm37mm9NCBIm37
MGSCv361734,580,788 - 34,587,281 (+)NCBImm8
Celera1738,068,927 - 38,075,454 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hspa1l
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10741
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.