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Gene: Htr2c (5-hydroxytryptamine (serotonin) receptor 2C) Mus musculus
Symbol: Htr2c
Name: 5-hydroxytryptamine (serotonin) receptor 2C
Description: Exhibits G protein-coupled serotonin receptor activity. Involved in several processes, including behavioral fear response; phospholipase C-activating G protein-coupled receptor signaling pathway; and positive regulation of fat cell differentiation. Predicted to localize to dendrite; external side of plasma membrane; and integral component of plasma membrane. Used to study Prader-Willi syndrome and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in bipolar disorder; obesity; and schizophrenia. Is expressed in several structures, including brain; exocrine gland; large intestine; testis; and thymus. Orthologous to human HTR2C (5-hydroxytryptamine receptor 2C).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5-HT-1C; 5-HT-2C; 5-HT1C; 5-HT2C; 5-HT2C receptor; 5-HT2cR; 5-HTR2C; 5-hydroxytryptamine receptor 1C; 5-hydroxytryptamine receptor 2C; 5HT1c; Htr1c; serotonin receptor 2C; SR1
Homo sapiens (human) : HTR2C (5-hydroxytryptamine receptor 2C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Htr2c (5-hydroxytryptamine receptor 2C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr2c (5-hydroxytryptamine receptor 2C)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR2C (5-hydroxytryptamine receptor 2C)
Canis lupus familiaris (dog) : HTR2C (5-hydroxytryptamine receptor 2C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htr2c (5-hydroxytryptamine receptor 2C)
Sus scrofa (pig) : HTR2C (5-hydroxytryptamine receptor 2C)
Chlorocebus sabaeus (African green monkey) : HTR2C (5-hydroxytryptamine receptor 2C)
Heterocephalus glaber (naked mole-rat) : Htr2c (5-hydroxytryptamine receptor 2C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 EnsemblX146,962,513 - 147,197,277 (+)EnsemblGRCm38mm10GRCm38
GRCm38X146,962,464 - 147,197,277 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X143,397,056 - 143,631,820 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X142,208,881 - 142,443,644 (+)NCBImm8
CeleraX130,902,904 - 131,136,225 (+)NCBICelera
Cytogenetic MapXF2NCBI
cM MapX68.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Htr2c
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10748
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.