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Gene: Htr2c (5-hydroxytryptamine (serotonin) receptor 2C) Mus musculus
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Symbol: Htr2c
Name: 5-hydroxytryptamine (serotonin) receptor 2C
Description: Exhibits G protein-coupled serotonin receptor activity. Involved in several processes, including behavioral fear response; phospholipase C-activating G protein-coupled receptor signaling pathway; and positive regulation of fat cell differentiation. Predicted to localize to dendrite; external side of plasma membrane; and integral component of plasma membrane. Used to study Prader-Willi syndrome and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in bipolar disorder; obesity; and schizophrenia. Is expressed in several structures, including brain; exocrine gland; large intestine; testis; and thymus. Orthologous to human HTR2C (5-hydroxytryptamine receptor 2C).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5-HT-1C; 5-HT-2C; 5-HT1C; 5-HT2C; 5-HT2C receptor; 5-HT2cR; 5-HTR2C; 5-hydroxytryptamine receptor 1C; 5-hydroxytryptamine receptor 2C; 5HT1c; Htr1c; serotonin receptor 2C; SR1
Orthologs:
Homo sapiens (human) : HTR2C (5-hydroxytryptamine receptor 2C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Htr2c (5-hydroxytryptamine receptor 2C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr2c (5-hydroxytryptamine receptor 2C)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR2C (5-hydroxytryptamine receptor 2C)
Canis lupus familiaris (dog) : HTR2C (5-hydroxytryptamine receptor 2C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htr2c (5-hydroxytryptamine receptor 2C)
Sus scrofa (pig) : HTR2C (5-hydroxytryptamine receptor 2C)
Chlorocebus sabaeus (African green monkey) : HTR2C (5-hydroxytryptamine receptor 2C)
Heterocephalus glaber (naked mole-rat) : Htr2c (5-hydroxytryptamine receptor 2C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 EnsemblX146,962,513 - 147,197,277 (+)EnsemblGRCm38mm10GRCm38
GRCm38X146,962,464 - 147,197,277 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X143,397,056 - 143,631,820 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X142,208,881 - 142,443,644 (+)NCBImm8
CeleraX130,902,904 - 131,136,225 (+)NCBICelera
Cytogenetic MapXF2NCBI
cM MapX68.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Htr2c
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10748
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.