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Gene: Htr3a (5-hydroxytryptamine (serotonin) receptor 3A) Mus musculus
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Symbol: Htr3a
Name: 5-hydroxytryptamine (serotonin) receptor 3A
Description: Exhibits identical protein binding activity. Predicted to contribute to extracellular ligand-gated ion channel activity. Predicted to be involved in several processes, including chemical synaptic transmission; positive regulation of ion transmembrane transporter activity; and regulation of membrane potential. Predicted to localize to several cellular components, including the cleavage furrow; integral component of synaptic membrane; and serotonin-activated cation-selective channel complex. Human ortholog(s) of this gene implicated in dyspepsia and irritable bowel syndrome. Is expressed in several structures, including central nervous system; eye; gallbladder; genitourinary system; and gut. Orthologous to human HTR3A (5-hydroxytryptamine receptor 3A); INTERACTS WITH 1,1,1-trichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5-HT-3; 5-HT3; 5-HT3 receptor; 5-HT3-A; 5-HT3A; 5-HT3R; 5-hydroxytryptamine receptor 3; 5-hydroxytryptamine receptor 3A; 5HT3 serotonin receptor; serotonin receptor 3A; serotonin-gated ion channel receptor
Orthologs:
Homo sapiens (human) : HTR3A (5-hydroxytryptamine receptor 3A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Htr3a (5-hydroxytryptamine receptor 3A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr3a (5-hydroxytryptamine receptor 3A)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR3A (5-hydroxytryptamine receptor 3A)
Canis lupus familiaris (dog) : HTR3A (5-hydroxytryptamine receptor 3A)
Sus scrofa (pig) : HTR3A (5-hydroxytryptamine receptor 3A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl948,899,213 - 48,911,099 (-)Ensembl
GRCm38948,899,213 - 48,911,152 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37948,707,318 - 48,719,204 (-)NCBIGRCm37mm9NCBIm37
MGSCv36948,651,146 - 48,662,968 (-)NCBImm8
Celera946,196,535 - 46,208,676 (-)NCBICelera
Cytogenetic Map9 A5.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Htr3a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10749
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.