Gene: Igf1 (insulin-like growth factor 1) Mus musculus
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Symbol: Igf1
Name: insulin-like growth factor 1
Description: This gene encodes a member of the insulin-like growth factor (IGF) family of proteins that promote growth and development during fetal and postnatal life. This gene is predominantly expressed in the liver and the encoded protein undergoes proteolytic processing to generate a disulfide-linked mature polypeptide. Transgenic disruption of this gene in mice results in reduced postnatal survival and severe growth retardation. Mice lacking the encoded protein exhibit generalized organ hypoplasia including underdevelopment of the central nervous system and developmental defects in bone, muscle and reproductive systems. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C730016P09Rik; Igf-1; Igf-I; insulin-like growth factor I; somatomedin
Orthologs:
Homo sapiens (human) : IGF1 (insulin like growth factor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Igf1 (insulin-like growth factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igf1 (insulin like growth factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IGF1 (insulin like growth factor 1)
Canis lupus familiaris (dog) : IGF1 (insulin like growth factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igf1 (insulin like growth factor 1)
Sus scrofa (pig) : IGF1 (insulin like growth factor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381087,858,265 - 87,937,047 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371087,321,801 - 87,399,792 (+)NCBIGRCm37mm9NCBIm37
MGSCv361087,289,200 - 87,361,600 (+)NCBImm8
Celera1089,837,923 - 89,916,340 (+)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1043.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences