Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Il5 (interleukin 5) Mus musculus
Symbol: Il5
Name: interleukin 5
Description: Exhibits cytokine activity. Involved in positive regulation of immunoglobulin secretion; positive regulation of peptidyl-tyrosine phosphorylation; and regulation of transcription, DNA-templated. Localizes to extracellular space. Is expressed in colon; thymus; and thymus primordium. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL5 (interleukin 5); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; interleukin-4 signaling pathway; interleukin-5 signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B-cell growth factor II; BCGF-II; cytotoxic T-lymphocyte inducer; eosinophil differentiation factor; Il-5; interleukin-5; T-cell replacing factor; TRF
Homo sapiens (human) : IL5 (interleukin 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il5 (interleukin 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il5 (interleukin 5)
Pan paniscus (bonobo/pygmy chimpanzee) : IL5 (interleukin 5)
Canis lupus familiaris (dog) : IL5 (interleukin 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il5 (interleukin 5)
Sus scrofa (pig) : IL5 (interleukin 5)
Chlorocebus sabaeus (African green monkey) : IL5 (interleukin 5)
Heterocephalus glaber (naked mole-rat) : Il5 (interleukin 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1153,720,794 - 53,725,106 (+)EnsemblGRCm38mm10GRCm38
GRCm381153,720,794 - 53,725,103 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371153,534,296 - 53,538,605 (+)NCBIGRCm37mm9NCBIm37
MGSCv361153,564,217 - 53,568,526 (+)NCBImm8
Celera1158,300,334 - 58,304,644 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Il5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10799
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.