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Gene: Ins1 (insulin I) Mus musculus
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Symbol: Ins1
Name: insulin I
Description: Predicted to have chaperone binding activity; insulin receptor binding activity; and protease binding activity. Predicted to be involved in several processes, including glucose homeostasis; positive regulation of protein phosphorylation; and regulation of gene expression. Localizes to the cytosol. Predicted to colocalize with the cytoplasm. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in diabetic retinopathy; glucose metabolism disease (multiple); insulinoma; and pancreatic cancer. Is expressed in several structures, including gut; trunk; and yolk sac. Orthologous to several human genes including INS (insulin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Ins-1; Ins2-rs1; insulin-1
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1952,264,297 - 52,265,476 (+)Ensembl
GRCm381952,264,297 - 52,265,015 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371952,338,813 - 52,339,966 (+)NCBIGRCm37mm9NCBIm37
MGSCv361952,317,762 - 52,318,343 (+)NCBImm8
Celera1954,451,492 - 54,452,645 (+)NCBICelera
Cytogenetic Map19 D2NCBI
cM Map1946.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ins1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10811
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.