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Gene: Kcnj8 (potassium inwardly-rectifying channel, subfamily J, member 8) Mus musculus
Symbol: Kcnj8
Name: potassium inwardly-rectifying channel, subfamily J, member 8
Description: Predicted to have ATP binding activity; sulfonylurea receptor binding activity; and voltage-gated potassium channel activity. Involved in several processes, including defense response to virus; response to exogenous dsRNA; and response to lipopolysaccharide. Localizes to the myofibril. Used to study coronary artery disease. Is expressed in genitourinary system and heart. Orthologous to human KCNJ8 (potassium inwardly rectifying channel subfamily J member 8); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI448900; ATP-sensitive inward rectifier potassium channel 8; gnite; inward rectifier K(+) channel Kir6.1; inwardly rectifier K(+) channel Kir6.1; Kir6.1; potassium channel, inwardly rectifying subfamily J member 8; slmbr; sltr; uKATP-1
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl6142,564,837 - 142,571,614 (-)Ensembl
GRCm386142,564,837 - 142,571,614 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376142,513,459 - 142,519,876 (-)NCBIGRCm37mm9NCBIm37
MGSCv366142,522,161 - 142,528,581 (-)NCBImm8
Celera6145,626,686 - 145,633,104 (-)NCBICelera
Cytogenetic Map6 G2NCBI
cM Map674.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kcnj8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10835
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.