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Gene: L1cam (L1 cell adhesion molecule) Mus musculus
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Symbol: L1cam
Name: L1 cell adhesion molecule
Description: Exhibits several functions, including identical protein binding activity; integrin binding activity; and sialic acid binding activity. Involved in several processes, including cell-cell adhesion mediated by integrin; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and homophilic cell adhesion via plasma membrane adhesion molecules. Localizes to external side of plasma membrane; presynaptic membrane; and terminal bouton. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and urinary system. Used to study MASA syndrome. Human ortholog(s) of this gene implicated in MASA syndrome; hydrocephalus; ovarian carcinoma; pancreatic cancer; and schizophrenia. Orthologous to human L1CAM (L1 cell adhesion molecule); INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD171; L1; L1-NCAM; N-CAM-L1; NCAM-L1; neural cell adhesion molecule L1
Orthologs:
Homo sapiens (human) : L1CAM (L1 cell adhesion molecule)  HGNC  Alliance
Rattus norvegicus (Norway rat) : L1cam (L1 cell adhesion molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : L1cam (L1 cell adhesion molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : L1CAM (L1 cell adhesion molecule)
Canis lupus familiaris (dog) : L1CAM (L1 cell adhesion molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : L1cam (L1 cell adhesion molecule)
Sus scrofa (pig) : L1CAM (L1 cell adhesion molecule)
Chlorocebus sabaeus (African green monkey) : L1CAM (L1 cell adhesion molecule)
Heterocephalus glaber (naked mole-rat) : L1cam (L1 cell adhesion molecule)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 EnsemblX73,853,778 - 73,896,105 (-)EnsemblGRCm38mm10GRCm38
GRCm38X73,853,778 - 73,880,838 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X71,099,119 - 71,126,173 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X70,107,755 - 70,122,524 (-)NCBImm8
CeleraX65,106,167 - 65,133,066 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on L1cam
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10850
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.