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Gene: L1cam (L1 cell adhesion molecule) Mus musculus
Symbol: L1cam
Name: L1 cell adhesion molecule
Description: Exhibits several functions, including identical protein binding activity; integrin binding activity; and sialic acid binding activity. Involved in several processes, including cell-cell adhesion mediated by integrin; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and homophilic cell adhesion via plasma membrane adhesion molecules. Localizes to external side of plasma membrane; presynaptic membrane; and terminal bouton. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and urinary system. Used to study MASA syndrome. Human ortholog(s) of this gene implicated in MASA syndrome; hydrocephalus; ovarian carcinoma; pancreatic cancer; and schizophrenia. Orthologous to human L1CAM (L1 cell adhesion molecule); INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD171; L1; L1-NCAM; N-CAM-L1; NCAM-L1; neural cell adhesion molecule L1
Homo sapiens (human) : L1CAM (L1 cell adhesion molecule)  HGNC  Alliance
Rattus norvegicus (Norway rat) : L1cam (L1 cell adhesion molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : L1cam (L1 cell adhesion molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : L1CAM (L1 cell adhesion molecule)
Canis lupus familiaris (dog) : L1CAM (L1 cell adhesion molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : L1cam (L1 cell adhesion molecule)
Sus scrofa (pig) : L1CAM (L1 cell adhesion molecule)
Chlorocebus sabaeus (African green monkey) : L1CAM (L1 cell adhesion molecule)
Heterocephalus glaber (naked mole-rat) : L1cam (L1 cell adhesion molecule)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 EnsemblX73,853,778 - 73,896,105 (-)EnsemblGRCm38mm10GRCm38
GRCm38X73,853,778 - 73,880,838 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X71,099,119 - 71,126,173 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X70,107,755 - 70,122,524 (-)NCBImm8
CeleraX65,106,167 - 65,133,066 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on L1cam
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10850
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.