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Gene: Lamp2 (lysosomal-associated membrane protein 2) Mus musculus
Symbol: Lamp2
Name: lysosomal-associated membrane protein 2
Description: Exhibits protein domain specific binding activity. Involved in several processes, including muscle cell cellular homeostasis; protein stabilization; and protein targeting to lysosome involved in chaperone-mediated autophagy. Localizes to bounding membrane of organelle. Predicted to colocalize with membrane raft. Used to study Danon disease. Human ortholog(s) of this gene implicated in Danon disease and hypertrophic cardiomyopathy. Is expressed in central nervous system; lung; retina; and yolk sac endoderm. Orthologous to human LAMP2 (lysosomal associated membrane protein 2); PARTICIPATES IN chaperone mediated autophagy pathway; autophagy pathway; tuberculosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD107 antigen-like family member B; CD107b; Lamp II; Lamp-2; Lamp-2a; Lamp-2b; Lamp-2c; LGP-B; lysosomal membrane glycoprotein 2; lysosomal membrane glycoprotein type B; lysosome-associated membrane glycoprotein 2; lysosome-associated membrane protein 2; lysosome-associated membrane protein-2; Mac3
Homo sapiens (human) : LAMP2 (lysosomal associated membrane protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lamp2 (lysosomal-associated membrane protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lamp2 (lysosomal associated membrane protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LAMP2 (lysosomal associated membrane protein 2)
Canis lupus familiaris (dog) : LAMP2 (lysosomal associated membrane protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lamp2 (lysosomal associated membrane protein 2)
Sus scrofa (pig) : LAMP2 (lysosomal associated membrane protein 2)
Chlorocebus sabaeus (African green monkey) : LAMP2 (lysosomal associated membrane protein 2)
Heterocephalus glaber (naked mole-rat) : Lamp2 (lysosomal associated membrane protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 EnsemblX38,401,357 - 38,456,454 (-)EnsemblGRCm38mm10GRCm38
GRCm38X38,399,647 - 38,456,460 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X35,758,241 - 35,809,632 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X34,649,691 - 34,701,082 (-)NCBImm8
CeleraX26,051,798 - 26,103,095 (-)NCBICelera
Cytogenetic MapXA3.3NCBI
cM MapX22.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lamp2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10857
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.