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Gene: Lhcgr (luteinizing hormone/choriogonadotropin receptor) Mus musculus
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Symbol: Lhcgr
Name: luteinizing hormone/choriogonadotropin receptor
Description: Exhibits choriogonadotropin hormone binding activity and choriogonadotropin hormone receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; regulation of cellular biosynthetic process; and reproductive structure development. Localizes to integral component of plasma membrane. Is expressed in early conceptus; medulla oblongata; medulla oblongata basal plate ventricular layer; oocyte; and testis. Human ortholog(s) of this gene implicated in Leydig cell tumor; breast cancer; familial male-limited precocious puberty; and gonadal disease. Orthologous to human LHCGR (luteinizing hormone/choriogonadotropin receptor); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; luteinizing hormone signaling pathway; peptide and protein hormone signaling pathway; INTERACTS WITH 1,2-dichloroethane; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gpcr19; Gpcr19-rs1; L; LH; LH-R; LH/CG-R; Lhr; LSH-R; luteinizing hormone receptor; lutropin-choriogonadotropic hormone receptor
Orthologs:
Homo sapiens (human) : LHCGR (luteinizing hormone/choriogonadotropin receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Canis lupus familiaris (dog) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
Sus scrofa (pig) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Chlorocebus sabaeus (African green monkey) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Heterocephalus glaber (naked mole-rat) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1788,716,481 - 88,791,990 (-)EnsemblGRCm38mm10GRCm38
GRCm381788,716,384 - 88,792,059 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371789,140,889 - 89,191,316 (-)NCBIGRCm37mm9NCBIm37
MGSCv361788,649,875 - 88,700,302 (-)NCBImm8
Celera1793,149,952 - 93,199,996 (-)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1758.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lhcgr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10870
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.