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Gene: Lhcgr (luteinizing hormone/choriogonadotropin receptor) Mus musculus
Symbol: Lhcgr
Name: luteinizing hormone/choriogonadotropin receptor
Description: Exhibits choriogonadotropin hormone binding activity and choriogonadotropin hormone receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; regulation of cellular biosynthetic process; and reproductive structure development. Localizes to integral component of plasma membrane. Is expressed in early conceptus; medulla oblongata; medulla oblongata basal plate ventricular layer; oocyte; and testis. Human ortholog(s) of this gene implicated in Leydig cell tumor; breast cancer; familial male-limited precocious puberty; and gonadal disease. Orthologous to human LHCGR (luteinizing hormone/choriogonadotropin receptor); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; luteinizing hormone signaling pathway; peptide and protein hormone signaling pathway; INTERACTS WITH 1,2-dichloroethane; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gpcr19; Gpcr19-rs1; L; LH; LH-R; LH/CG-R; Lhr; LSH-R; luteinizing hormone receptor; lutropin-choriogonadotropic hormone receptor
Homo sapiens (human) : LHCGR (luteinizing hormone/choriogonadotropin receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Canis lupus familiaris (dog) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
Sus scrofa (pig) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Chlorocebus sabaeus (African green monkey) : LHCGR (luteinizing hormone/choriogonadotropin receptor)
Heterocephalus glaber (naked mole-rat) : Lhcgr (luteinizing hormone/choriogonadotropin receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1788,716,481 - 88,791,990 (-)EnsemblGRCm38mm10GRCm38
GRCm381788,716,384 - 88,792,059 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371789,140,889 - 89,191,316 (-)NCBIGRCm37mm9NCBIm37
MGSCv361788,649,875 - 88,700,302 (-)NCBImm8
Celera1793,149,952 - 93,199,996 (-)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1758.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lhcgr
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10870
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.