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Gene: Lipe (lipase, hormone sensitive) Mus musculus
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Symbol: Lipe
Name: lipase, hormone sensitive
Description: Exhibits protein kinase binding activity; serine hydrolase activity; and triglyceride lipase activity. Involved in diacylglycerol catabolic process; long-chain fatty acid catabolic process; and triglyceride catabolic process. Localizes to the cytosol and lipid droplet. Human ortholog(s) of this gene implicated in arteriosclerosis; familial partial lipodystrophy type 6; and hypertension. Orthologous to human LIPE (lipase E, hormone sensitive type); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH (25R)-cholest-5-ene-3beta,26-diol; (R)-adrenaline; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4933403G17Rik; hormone-sensitive lipase; HSL
Orthologs:
Homo sapiens (human) : LIPE (lipase E, hormone sensitive type)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lipe (lipase E, hormone sensitive type)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lipe (lipase E, hormone sensitive type)
Pan paniscus (bonobo/pygmy chimpanzee) : LIPE (lipase E, hormone sensitive type)
Canis lupus familiaris (dog) : LIPE (lipase E, hormone sensitive type)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lipe (lipase E, hormone sensitive type)
Sus scrofa (pig) : LIPE (lipase E, hormone sensitive type)
Chlorocebus sabaeus (green monkey) : LIPE (lipase E, hormone sensitive type)
Heterocephalus glaber (naked mole-rat) : Lipe (lipase E, hormone sensitive type)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl725,379,527 - 25,398,710 (-)Ensembl
GRCm38725,379,527 - 25,398,486 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37726,164,546 - 26,181,006 (-)NCBIGRCm37mm9NCBIm37
MGSCv36725,088,287 - 25,104,747 (-)NCBImm8
Celera719,994,853 - 20,011,313 (-)NCBICelera
Cytogenetic Map7 A3NCBI
cM Map713.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lipe
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10872
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.