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Gene: Mpz (myelin protein zero) Mus musculus
Symbol: Mpz
Name: myelin protein zero
Description: Involved in cell-cell junction maintenance and myelination. Predicted to localize to the basolateral plasma membrane; lysosome; and rough endoplasmic reticulum. Used to study Charcot-Marie-Tooth disease type 1B; Charcot-Marie-Tooth disease type 3; PCWH syndrome; and neuropathy. Human ortholog(s) of this gene implicated in neuromuscular disease (multiple). Is expressed in nervous system; nose; and turbinate bone primordium. Orthologous to human MPZ (myelin protein zero).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Mpp; myelin peripheral protein; myelin protein P0; P-zero; P0
Homo sapiens (human) : MPZ (myelin protein zero)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mpz (myelin protein zero)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mpz (myelin protein zero)
Pan paniscus (bonobo/pygmy chimpanzee) : MPZ (myelin protein zero)
Canis lupus familiaris (dog) : MPZ (myelin protein zero)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mpz (myelin protein zero)
Sus scrofa (pig) : MPZ (myelin protein zero)
Chlorocebus sabaeus (African green monkey) : MPZ (myelin protein zero)
Heterocephalus glaber (naked mole-rat) : Mpz (myelin protein zero)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1171,150,711 - 171,161,130 (+)EnsemblGRCm38mm10GRCm38
GRCm381171,150,713 - 171,161,130 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371173,080,844 - 173,091,254 (+)NCBIGRCm37mm9NCBIm37
MGSCv361172,987,388 - 172,997,798 (+)NCBImm8
Celera1173,598,959 - 173,609,357 (+)NCBICelera
Cytogenetic Map1 H3NCBI
cM Map179.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mpz
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10917
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.