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Gene: Abcc1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 1) Mus musculus
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Symbol: Abcc1
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Description: Exhibits transmembrane transporter activity. Involved in several processes, including cellular response to amyloid-beta; export across plasma membrane; and leukotriene transport. Localizes to the integral component of plasma membrane. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease. Is expressed in several structures, including embryo mesenchyme; genitourinary system; hemolymphoid system; nervous system; and nose. Orthologous to human ABCC1 (ATP binding cassette subfamily C member 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Abcc1a; Abcc1b; ATP-binding cassette sub-family C member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1a; ATP-binding cassette, sub-family C (CFTR/MRP), member 1b; glutathione-S-conjugate-translocating ATPase ABCC1; leukotriene C(4) transporter; LTC4 transporter; Mdrap; MRP; Mrp1; multidrug resistance-associated protein 1; multiple drug resistance-associated protein
Orthologs:
Homo sapiens (human) : ABCC1 (ATP binding cassette subfamily C member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Abcc1 (ATP binding cassette subfamily C member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcc1 (ATP binding cassette subfamily C member 1)
Canis lupus familiaris (dog) : ABCC1 (ATP binding cassette subfamily C member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc1 (ATP binding cassette subfamily C member 1)
Sus scrofa (pig) : ABCC1 (ATP binding cassette subfamily C member 1)
Chlorocebus sabaeus (African green monkey) : ABCC1 (ATP binding cassette subfamily C member 1)
Heterocephalus glaber (naked mole-rat) : Abcc1 (ATP binding cassette subfamily C member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1614,361,558 - 14,475,737 (+)EnsemblGRCm38mm10GRCm38
GRCm381614,361,453 - 14,474,878 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371614,361,653 - 14,474,968 (+)NCBIGRCm37mm9NCBIm37
MGSCv361614,275,138 - 14,388,453 (+)NCBImm8
Celera1614,966,079 - 15,077,783 (+)NCBICelera
Cytogenetic Map16A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Abcc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10919
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.