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Gene: Myb (myeloblastosis oncogene) Mus musculus
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Symbol: Myb
Name: myeloblastosis oncogene
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and WD40-repeat domain binding activity. Involved in several processes, including cellular response to cytokine stimulus; embryonic digestive tract development; and hematopoietic or lymphoid organ development. Localizes to the cytosol and nucleus. Used to study essential thrombocythemia and myelofibrosis. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human MYB (MYB proto-oncogene, transcription factor); PARTICIPATES IN interleukin-4 signaling pathway; INTERACTS WITH (R)-pantothenic acid; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI550390; c-myb; gag-myb protein; M16449; MGC18531; myb proto-oncogene protein; myeloblastosis proto-oncogene product; proto-oncogene c-Myb; transcriptional activator Myb; tumor-specific myb protein
Orthologs:
Homo sapiens (human) : MYB (MYB proto-oncogene, transcription factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Myb (MYB proto-oncogene, transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myb (MYB proto-oncogene, transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : MYB (MYB proto-oncogene, transcription factor)
Canis lupus familiaris (dog) : MYB (MYB proto-oncogene, transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myb (MYB proto-oncogene, transcription factor)
Sus scrofa (pig) : MYB (MYB proto-oncogene, transcription factor)
Chlorocebus sabaeus (green monkey) : MYB (MYB proto-oncogene, transcription factor)
Heterocephalus glaber (naked mole-rat) : Myb (MYB proto-oncogene, transcription factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1021,124,935 - 21,160,984 (-)Ensembl
GRCm381021,124,930 - 21,160,984 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371020,844,736 - 20,880,790 (-)NCBIGRCm37mm9NCBIm37
MGSCv361020,814,352 - 20,850,400 (-)NCBImm8
Celera1021,025,990 - 21,061,964 (-)NCBICelera
Cytogenetic Map10 A3NCBI
cM Map109.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Myb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10933
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.