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Gene: Myb (myeloblastosis oncogene) Mus musculus
Symbol: Myb
Name: myeloblastosis oncogene
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and WD40-repeat domain binding activity. Involved in several processes, including cellular response to cytokine stimulus; embryonic digestive tract development; and hematopoietic or lymphoid organ development. Localizes to the cytosol and nucleus. Used to study essential thrombocythemia and myelofibrosis. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human MYB (MYB proto-oncogene, transcription factor); PARTICIPATES IN interleukin-4 signaling pathway; INTERACTS WITH (R)-pantothenic acid; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI550390; c-myb; gag-myb protein; M16449; MGC18531; myb proto-oncogene protein; myeloblastosis proto-oncogene product; proto-oncogene c-Myb; transcriptional activator Myb; tumor-specific myb protein
Homo sapiens (human) : MYB (MYB proto-oncogene, transcription factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Myb (MYB proto-oncogene, transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myb (MYB proto-oncogene, transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : MYB (MYB proto-oncogene, transcription factor)
Canis lupus familiaris (dog) : MYB (MYB proto-oncogene, transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myb (MYB proto-oncogene, transcription factor)
Sus scrofa (pig) : MYB (MYB proto-oncogene, transcription factor)
Chlorocebus sabaeus (green monkey) : MYB (MYB proto-oncogene, transcription factor)
Heterocephalus glaber (naked mole-rat) : Myb (MYB proto-oncogene, transcription factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1021,124,935 - 21,160,984 (-)Ensembl
GRCm381021,124,930 - 21,160,984 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371020,844,736 - 20,880,790 (-)NCBIGRCm37mm9NCBIm37
MGSCv361020,814,352 - 20,850,400 (-)NCBImm8
Celera1021,025,990 - 21,061,964 (-)NCBICelera
Cytogenetic Map10 A3NCBI
cM Map109.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Myb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10933
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.