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Gene: Ngf (nerve growth factor) Mus musculus
Symbol: Ngf
Name: nerve growth factor
Description: Exhibits transmembrane receptor protein tyrosine kinase activator activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of macromolecule metabolic process; and positive regulation of neuron differentiation. Localizes to neuron projection terminus. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; end stage renal failure; hereditary sensory and autonomic neuropathy type 5; interstitial cystitis; and neurogenic bladder. Orthologous to human NGF (nerve growth factor); PARTICIPATES IN apoptotic cell death pathway; mitogen activated protein kinase signaling pathway; neurotrophic factor signaling pathway; INTERACTS WITH 1-chloro-2,4,6-trinitrobenzene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: beta-nerve growth factor; beta-NGF; nerve growth factor, beta; Ngfb
Homo sapiens (human) : NGF (nerve growth factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ngf (nerve growth factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ngf (nerve growth factor)
Pan paniscus (bonobo/pygmy chimpanzee) : NGF (nerve growth factor)
Canis lupus familiaris (dog) : NGF (nerve growth factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ngf (nerve growth factor)
Sus scrofa (pig) : NGF (nerve growth factor)
Chlorocebus sabaeus (African green monkey) : NGF (nerve growth factor)
Heterocephalus glaber (naked mole-rat) : Ngf (nerve growth factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl3102,469,919 - 102,521,013 (+)EnsemblGRCm38mm10GRCm38
GRCm383102,469,919 - 102,521,013 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373102,273,851 - 102,324,936 (+)NCBIGRCm37mm9NCBIm37
MGSCv363102,598,989 - 102,650,066 (+)NCBImm8
Celera3104,674,123 - 104,724,621 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map345.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ngf
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10978
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.