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Gene: Ngf (nerve growth factor) Mus musculus
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Symbol: Ngf
Name: nerve growth factor
Description: Exhibits transmembrane receptor protein tyrosine kinase activator activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of macromolecule metabolic process; and positive regulation of neuron differentiation. Localizes to neuron projection terminus. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; end stage renal failure; hereditary sensory and autonomic neuropathy type 5; interstitial cystitis; and neurogenic bladder. Orthologous to human NGF (nerve growth factor); PARTICIPATES IN apoptotic cell death pathway; mitogen activated protein kinase signaling pathway; neurotrophic factor signaling pathway; INTERACTS WITH 1-chloro-2,4,6-trinitrobenzene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: beta-nerve growth factor; beta-NGF; nerve growth factor, beta; Ngfb
Orthologs:
Homo sapiens (human) : NGF (nerve growth factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ngf (nerve growth factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ngf (nerve growth factor)
Pan paniscus (bonobo/pygmy chimpanzee) : NGF (nerve growth factor)
Canis lupus familiaris (dog) : NGF (nerve growth factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ngf (nerve growth factor)
Sus scrofa (pig) : NGF (nerve growth factor)
Chlorocebus sabaeus (African green monkey) : NGF (nerve growth factor)
Heterocephalus glaber (naked mole-rat) : Ngf (nerve growth factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl3102,469,919 - 102,521,013 (+)EnsemblGRCm38mm10GRCm38
GRCm383102,469,919 - 102,521,013 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373102,273,851 - 102,324,936 (+)NCBIGRCm37mm9NCBIm37
MGSCv363102,598,989 - 102,650,066 (+)NCBImm8
Celera3104,674,123 - 104,724,621 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map345.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ngf
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10978
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.