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Gene: Ngfr (nerve growth factor receptor (TNFR superfamily, member 16)) Mus musculus
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Symbol: Ngfr
Name: nerve growth factor receptor (TNFR superfamily, member 16)
Description: Exhibits Rab GTPase binding activity; death receptor activity; and nerve growth factor binding activity. Involved in several processes, including circadian regulation of gene expression; nervous system development; and regulation of signal transduction. Localizes to several cellular components, including cell surface; cell-cell junction; and postsynaptic density. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and mental depression. Orthologous to human NGFR (nerve growth factor receptor); PARTICIPATES IN neurotrophic factor signaling pathway; INTERACTS WITH (+)-pilocarpine; (R)-lipoic acid; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LNGFR; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; NGF receptor; p75; p75 neurotrophin receptor; p75NGFR; p75NTR; Tnfrsf16; tumor necrosis factor receptor superfamily member 16
Orthologs:
Homo sapiens (human) : NGFR (nerve growth factor receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ngfr (nerve growth factor receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ngfr (nerve growth factor receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : NGFR (nerve growth factor receptor)
Canis lupus familiaris (dog) : NGFR (nerve growth factor receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ngfr (nerve growth factor receptor)
Sus scrofa (pig) : NGFR (nerve growth factor receptor)
Chlorocebus sabaeus (African green monkey) : NGFR (nerve growth factor receptor)
Heterocephalus glaber (naked mole-rat) : Ngfr (nerve growth factor receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1195,568,818 - 95,587,735 (-)EnsemblGRCm38mm10GRCm38
GRCm381195,568,818 - 95,587,698 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371195,430,132 - 95,449,012 (-)NCBIGRCm37mm9NCBIm37
MGSCv361195,384,908 - 95,403,788 (-)NCBImm8
Celera11105,207,524 - 105,226,387 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ngfr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10983
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.