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Gene: Ngfr (nerve growth factor receptor (TNFR superfamily, member 16)) Mus musculus
Symbol: Ngfr
Name: nerve growth factor receptor (TNFR superfamily, member 16)
Description: Exhibits Rab GTPase binding activity; death receptor activity; and nerve growth factor binding activity. Involved in several processes, including circadian regulation of gene expression; nervous system development; and regulation of signal transduction. Localizes to several cellular components, including cell surface; cell-cell junction; and postsynaptic density. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and mental depression. Orthologous to human NGFR (nerve growth factor receptor); PARTICIPATES IN neurotrophic factor signaling pathway; INTERACTS WITH (+)-pilocarpine; (R)-lipoic acid; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LNGFR; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; NGF receptor; p75; p75 neurotrophin receptor; p75NGFR; p75NTR; Tnfrsf16; tumor necrosis factor receptor superfamily member 16
Homo sapiens (human) : NGFR (nerve growth factor receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ngfr (nerve growth factor receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ngfr (nerve growth factor receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : NGFR (nerve growth factor receptor)
Canis lupus familiaris (dog) : NGFR (nerve growth factor receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ngfr (nerve growth factor receptor)
Sus scrofa (pig) : NGFR (nerve growth factor receptor)
Chlorocebus sabaeus (African green monkey) : NGFR (nerve growth factor receptor)
Heterocephalus glaber (naked mole-rat) : Ngfr (nerve growth factor receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1195,568,818 - 95,587,735 (-)EnsemblGRCm38mm10GRCm38
GRCm381195,568,818 - 95,587,698 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371195,430,132 - 95,449,012 (-)NCBIGRCm37mm9NCBIm37
MGSCv361195,384,908 - 95,403,788 (-)NCBImm8
Celera11105,207,524 - 105,226,387 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ngfr
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10983
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.