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Gene: Npm1 (nucleophosmin 1) Mus musculus
Symbol: Npm1
Name: nucleophosmin 1
Description: Exhibits identical protein binding activity; protein N-terminus binding activity; and rRNA binding activity. Involved in several processes, including positive regulation of macromolecule metabolic process; rRNA-containing ribonucleoprotein complex export from nucleus; and regulation of gene expression. Localizes to several cellular components, including centrosome; nuclear lumen; and ribosomal subunit. Used to study myelodysplastic syndrome. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Is expressed in several structures, including central nervous system; early conceptus; oocyte; and small intestine crypt of lieberkuhn. Orthologous to human NPM1 (nucleophosmin 1); PARTICIPATES IN hypoxia inducible factor pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B23; MGC102162; MGC107291; NO38; Npm; nucleolar phosphoprotein B23; nucleolar protein NO38; nucleophosmin; numatrin
Homo sapiens (human) : NPM1 (nucleophosmin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Npm1 (nucleophosmin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Npm1 (nucleophosmin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NPM1 (nucleophosmin 1)
Canis lupus familiaris (dog) : NPM1 (nucleophosmin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Npm1 (nucleophosmin 1)
Sus scrofa (pig) : NPM1 (nucleophosmin 1)
Chlorocebus sabaeus (African green monkey) : NPM1 (nucleophosmin 1)
Heterocephalus glaber (naked mole-rat) : Npm1 (nucleophosmin 1)
more info ...
Related Pseudogenes: Gm12583   Gm13423   Gm14776   Gm17060   Gm17895   Gm17898   Gm17905   Gm17906   Gm17910   Gm17911   Gm17917   Gm17921   Gm17922   Gm17925   Gm5611   Gm6477   Gm7289   Gm9118  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1133,152,287 - 33,163,206 (-)EnsemblGRCm38mm10GRCm38
GRCm381133,152,498 - 33,164,142 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371133,052,511 - 33,063,056 (-)NCBIGRCm37mm9NCBIm37
MGSCv361133,052,511 - 33,063,056 (-)NCBImm8
Celera1135,564,831 - 35,575,324 (-)NCBICelera
Cytogenetic Map11A4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Npm1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11000
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.