Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Npr3 (natriuretic peptide receptor 3) Mus musculus
Analyze
Symbol: Npr3
Name: natriuretic peptide receptor 3
Description: Predicted to have several functions, including chloride ion binding activity; peptide receptor activity; and protein homodimerization activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; osteoclast proliferation; and positive regulation of urine volume. Predicted to localize to membrane and protein-containing complex. Used to study bone disease. Human ortholog(s) of this gene implicated in hypertension. Is expressed in several structures, including cardiovascular system; central nervous system; lung; sensory organ; and urinary system. Orthologous to human NPR3 (natriuretic peptide receptor 3); PARTICIPATES IN C-type natriuretic peptide signaling pathway; INTERACTS WITH 1,1-dichloroethene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ANP-C; ANPR-C; atrial natriuretic peptide clearance receptor; atrial natriuretic peptide receptor 3; atrial natriuretic peptide receptor type C; B430320C24Rik; C81222; EF-2; lgj; longjohn; Nppc receptor; NPR-C; stri; strigosus
Orthologs:
Homo sapiens (human) : NPR3 (natriuretic peptide receptor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Npr3 (natriuretic peptide receptor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Npr3 (natriuretic peptide receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NPR3 (natriuretic peptide receptor 3)
Canis lupus familiaris (dog) : NPR3 (natriuretic peptide receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Npr3 (natriuretic peptide receptor 3)
Sus scrofa (pig) : NPR3 (natriuretic peptide receptor 3)
Chlorocebus sabaeus (African green monkey) : NPR3 (natriuretic peptide receptor 3)
Heterocephalus glaber (naked mole-rat) : Npr3 (natriuretic peptide receptor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1511,839,896 - 11,907,287 (-)EnsemblGRCm38mm10GRCm38
GRCm381511,839,896 - 11,907,837 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371511,769,651 - 11,835,429 (-)NCBIGRCm37mm9NCBIm37
MGSCv361511,784,621 - 11,850,399 (-)NCBImm8
Celera1511,624,844 - 11,690,388 (-)NCBICelera
Cytogenetic Map15A1NCBI
cM Map155.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Npr3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11008
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-19
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.