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Gene: P2rx1 (purinergic receptor P2X, ligand-gated ion channel, 1) Mus musculus
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Symbol: P2rx1
Name: purinergic receptor P2X, ligand-gated ion channel, 1
Description: Exhibits cation channel activity and purinergic nucleotide receptor activity. Involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; regulation of ion transport; and serotonin secretion by platelet. Localizes to external side of plasma membrane and postsynaptic membrane. Is expressed in several structures, including bladder; foregut-midgut junction; heart; liver lobe; and midgut. Orthologous to human P2RX1 (purinergic receptor P2X 1); INTERACTS WITH 4-hydroxyphenyl retinamide; benzo[a]pyrene; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI323649; ATP receptor; BB122383; P2x; P2X purinoceptor 1; P2X1 receptor; Pdcd3; programmed cell death 3; RP-2
Orthologs:
Homo sapiens (human) : P2RX1 (purinergic receptor P2X 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : P2rx1 (purinergic receptor P2X 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2rx1 (purinergic receptor P2X 1)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX1 (purinergic receptor P2X 1)
Canis lupus familiaris (dog) : P2RX1 (purinergic receptor P2X 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx1 (purinergic receptor P2X 1)
Sus scrofa (pig) : P2RX1 (purinergic receptor P2X 1)
Chlorocebus sabaeus (African green monkey) : P2RX1 (purinergic receptor P2X 1)
Heterocephalus glaber (naked mole-rat) : P2rx1 (purinergic receptor P2X 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1172,999,103 - 73,015,200 (+)EnsemblGRCm38mm10GRCm38
GRCm381172,999,056 - 73,015,200 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371172,812,647 - 72,828,699 (+)NCBIGRCm37mm9NCBIm37
MGSCv361172,815,342 - 72,831,394 (+)NCBImm8
Celera1180,527,873 - 80,544,046 (+)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1145.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on P2rx1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11042
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.