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Gene: P2rx1 (purinergic receptor P2X, ligand-gated ion channel, 1) Mus musculus
Symbol: P2rx1
Name: purinergic receptor P2X, ligand-gated ion channel, 1
Description: Exhibits cation channel activity and purinergic nucleotide receptor activity. Involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; regulation of ion transport; and serotonin secretion by platelet. Localizes to external side of plasma membrane and postsynaptic membrane. Is expressed in several structures, including bladder; foregut-midgut junction; heart; liver lobe; and midgut. Orthologous to human P2RX1 (purinergic receptor P2X 1); INTERACTS WITH 4-hydroxyphenyl retinamide; benzo[a]pyrene; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI323649; ATP receptor; BB122383; P2x; P2X purinoceptor 1; P2X1 receptor; Pdcd3; programmed cell death 3; RP-2
Homo sapiens (human) : P2RX1 (purinergic receptor P2X 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : P2rx1 (purinergic receptor P2X 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2rx1 (purinergic receptor P2X 1)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX1 (purinergic receptor P2X 1)
Canis lupus familiaris (dog) : P2RX1 (purinergic receptor P2X 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx1 (purinergic receptor P2X 1)
Sus scrofa (pig) : P2RX1 (purinergic receptor P2X 1)
Chlorocebus sabaeus (African green monkey) : P2RX1 (purinergic receptor P2X 1)
Heterocephalus glaber (naked mole-rat) : P2rx1 (purinergic receptor P2X 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1172,999,103 - 73,015,200 (+)EnsemblGRCm38mm10GRCm38
GRCm381172,999,056 - 73,015,200 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371172,812,647 - 72,828,699 (+)NCBIGRCm37mm9NCBIm37
MGSCv361172,815,342 - 72,831,394 (+)NCBImm8
Celera1180,527,873 - 80,544,046 (+)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1145.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on P2rx1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11042
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.