Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pam (peptidylglycine alpha-amidating monooxygenase) Mus musculus
Symbol: Pam
Name: peptidylglycine alpha-amidating monooxygenase
Description: Predicted to have several functions, including metal ion binding activity; peptidylamidoglycolate lyase activity; and peptidylglycine monooxygenase activity. Predicted to be involved in several processes, including fatty acid primary amide biosynthetic process; peptide amidation; and response to zinc ion. Predicted to localize to several cellular components, including perikaryon; secretory granule membrane; and trans-Golgi network. Is expressed in several structures, including alimentary system; central nervous system; forelimb bud; limb interdigital region; and sensory organ. Orthologous to human PAM (peptidylglycine alpha-amidating monooxygenase); PARTICIPATES IN melanocortin system pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: peptidyl-glycine alpha-amidating monooxygenase; PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PRECURSOR (PAM); PHM
Homo sapiens (human) : PAM (peptidylglycine alpha-amidating monooxygenase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pam (peptidylglycine alpha-amidating monooxygenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pam (peptidylglycine alpha-amidating monooxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : PAM (peptidylglycine alpha-amidating monooxygenase)
Canis lupus familiaris (dog) : PAM (peptidylglycine alpha-amidating monooxygenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pam (peptidylglycine alpha-amidating monooxygenase)
Sus scrofa (pig) : PAM (peptidylglycine alpha-amidating monooxygenase)
Chlorocebus sabaeus (African green monkey) : PAM (peptidylglycine alpha-amidating monooxygenase)
Heterocephalus glaber (naked mole-rat) : Pam (peptidylglycine alpha-amidating monooxygenase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl197,795,114 - 98,095,646 (-)EnsemblGRCm38mm10GRCm38
GRCm38197,821,091 - 98,095,853 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37199,717,671 - 99,992,209 (-)NCBIGRCm37mm9NCBIm37
MGSCv36199,651,500 - 99,925,919 (-)NCBImm8
Celera1100,701,674 - 100,975,784 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map147.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pam
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11056
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.