Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pax6 (paired box 6) Mus musculus
Analyze
Symbol: Pax6
Name: paired box 6
Description: Exhibits several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; SMAD binding activity; and enzyme binding activity. Involved in several processes, including animal organ development; negative regulation of cell population proliferation; and nervous system development. Localizes to the nuclear chromatin. Used to study Peters anomaly; aniridia; cataract; and juvenile glaucoma. Human ortholog(s) of this gene implicated in eye disease (multiple); glucose intolerance; and paranoid schizophrenia. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; eye; and nose. Orthologous to human PAX6 (paired box 6).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1500038E17Rik; AEY11; Dey; Dickie's small eye; Gsfaey11; oculorhombin; paired box gene 6; paired box protein Pax-6; Pax-6; Sey; small eye
Orthologs:
Homo sapiens (human) : PAX6 (paired box 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pax6 (paired box 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pax6 (paired box 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PAX6 (paired box 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pax6 (paired box 6)
Sus scrofa (pig) : PAX6 (paired box 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl2105,668,900 - 105,697,364 (+)Ensembl
GRCm382105,668,896 - 105,698,410 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372105,516,602 - 105,537,226 (+)NCBIGRCm37mm9NCBIm37
MGSCv362105,477,284 - 105,497,908 (+)NCBImm8
Celera2106,890,276 - 106,918,747 (+)NCBICelera
Cytogenetic Map2 E3NCBI
cM Map255.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Pax6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11059
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.