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Gene: Pdgfra (platelet derived growth factor receptor, alpha polypeptide) Mus musculus
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Symbol: Pdgfra
Name: platelet derived growth factor receptor, alpha polypeptide
Description: Exhibits platelet-derived growth factor alpha-receptor activity and platelet-derived growth factor binding activity. Involved in several processes, including animal organ development; face morphogenesis; and protein phosphorylation. Localizes to several cellular components, including the Golgi apparatus; external side of plasma membrane; and microvillus. Used to study congenital diaphragmatic hernia. Human ortholog(s) of this gene implicated in hematologic cancer (multiple); hypereosinophilic syndrome; and pancreatic cancer. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; genitourinary system; and heart and pericardium. Orthologous to human PDGFRA (platelet derived growth factor receptor alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI115593; alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a; PDGF alpha chain; PDGF-R-alpha; Pdgfr-2; PDGFR-alpha; platelet-derived growth factor alpha receptor; platelet-derived growth factor receptor alpha
Orthologs:
Homo sapiens (human) : PDGFRA (platelet derived growth factor receptor alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pdgfra (platelet derived growth factor receptor alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdgfra (platelet derived growth factor receptor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : PDGFRA (platelet derived growth factor receptor alpha)
Canis lupus familiaris (dog) : PDGFRA (platelet derived growth factor receptor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdgfra (platelet derived growth factor receptor alpha)
Sus scrofa (pig) : PDGFRA (platelet derived growth factor receptor alpha)
Chlorocebus sabaeus (African green monkey) : PDGFRA (platelet derived growth factor receptor alpha)
Heterocephalus glaber (naked mole-rat) : Pdgfra (platelet derived growth factor receptor alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl575,152,292 - 75,198,215 (+)Ensembl
GRCm38575,151,322 - 75,198,206 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37575,548,316 - 75,594,229 (+)NCBIGRCm37mm9NCBIm37
MGSCv36575,434,045 - 75,479,893 (+)NCBImm8
Celera572,441,591 - 72,487,596 (+)NCBICelera
Cytogenetic Map5 C3.3NCBI
cM Map539.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pdgfra
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11069
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.