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Gene: Pnmt (phenylethanolamine-N-methyltransferase) Mus musculus
Symbol: Pnmt
Name: phenylethanolamine-N-methyltransferase
CRRD ID: 11126
Description: Predicted to have phenylethanolamine N-methyltransferase activity. Predicted to be involved in epinephrine biosynthetic process and norepinephrine metabolic process. Predicted to localize to several cellular components, including axon; dendrite; and perikaryon. Is expressed in adrenal gland; adrenal medulla; gland; medulla oblongata basal plate mantle layer; and metanephros. Human ortholog(s) of this gene implicated in Alzheimer's disease; hypertension; and multiple sclerosis. Orthologous to human PNMT (phenylethanolamine N-methyltransferase); PARTICIPATES IN alkaptonuria pathway; aromatic L-amino acid decarboxylase deficiency pathway; catecholamine biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; crocidolite asbestos.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: noradrenaline N-methyltransferase; Pe; Pent; phenylethanolamine N-methyltransferase; PNMTase
Homo sapiens (human) : PNMT (phenylethanolamine N-methyltransferase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pnmt (phenylethanolamine-N-methyltransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pnmt (phenylethanolamine N-methyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : PNMT (phenylethanolamine N-methyltransferase)
Canis lupus familiaris (dog) : PNMT (phenylethanolamine N-methyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pnmt (phenylethanolamine N-methyltransferase)
Sus scrofa (pig) : PNMT (phenylethanolamine N-methyltransferase)
Chlorocebus sabaeus (African green monkey) : PNMT (phenylethanolamine N-methyltransferase)
Heterocephalus glaber (naked mole-rat) : Pnmt (phenylethanolamine N-methyltransferase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391198,277,449 - 98,279,006 (+)NCBI
GRCm381198,386,623 - 98,388,180 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1198,386,450 - 98,388,181 (+)EnsemblGRCm38mm10GRCm38
MGSCv371198,247,946 - 98,249,411 (+)NCBIGRCm37mm9NCBIm37
MGSCv361198,202,722 - 98,204,187 (+)NCBImm8
Celera11108,040,856 - 108,042,321 (+)NCBICelera
Cytogenetic Map11DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pnmt
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11126
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.