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Gene: Ppp3cb (protein phosphatase 3, catalytic subunit, beta isoform) Mus musculus
Symbol: Ppp3cb
Name: protein phosphatase 3, catalytic subunit, beta isoform
Description: Exhibits calmodulin-dependent protein phosphatase activity. Involved in several processes, including cellular protein modification process; circulatory system development; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Localizes to the T-tubule; Z disc; and glutamatergic synapse. Human ortholog(s) of this gene implicated in aortic valve stenosis. Is expressed in heart; oocyte; ovary; and renal vasculature. Orthologous to human PPP3CB (protein phosphatase 3 catalytic subunit beta); PARTICIPATES IN calcineurin signaling pathway; dopamine signaling pathway; interleukin-12 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110063J16Rik; calmodulin-dependent calcineurin A subunit beta isoform; Calnb; CAM-PRP catalytic subunit; CNA beta; Cnab; CnAbeta; PP2BA beta; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
Homo sapiens (human) : PPP3CB (protein phosphatase 3 catalytic subunit beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ppp3cb (protein phosphatase 3 catalytic subunit beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppp3cb (protein phosphatase 3 catalytic subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : PPP3CB (protein phosphatase 3 catalytic subunit beta)
Canis lupus familiaris (dog) : PPP3CB (protein phosphatase 3 catalytic subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppp3cb (protein phosphatase 3 catalytic subunit beta)
Sus scrofa (pig) : PPP3CB (protein phosphatase 3 catalytic subunit beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381420,499,364 - 20,546,573 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371421,318,536 - 21,365,795 (-)NCBIGRCm37mm9NCBIm37
MGSCv361419,288,592 - 19,335,096 (-)NCBImm8
Celera1416,880,736 - 16,928,039 (-)NCBICelera
Cytogenetic Map14 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ppp3cb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11135
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.