Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ppp3cb (protein phosphatase 3, catalytic subunit, beta isoform) Mus musculus
Analyze
Symbol: Ppp3cb
Name: protein phosphatase 3, catalytic subunit, beta isoform
Description: Exhibits calmodulin-dependent protein phosphatase activity. Involved in several processes, including cellular protein modification process; circulatory system development; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Localizes to the T-tubule; Z disc; and glutamatergic synapse. Human ortholog(s) of this gene implicated in aortic valve stenosis. Is expressed in heart; oocyte; ovary; and renal vasculature. Orthologous to human PPP3CB (protein phosphatase 3 catalytic subunit beta); PARTICIPATES IN calcineurin signaling pathway; dopamine signaling pathway; interleukin-12 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110063J16Rik; calmodulin-dependent calcineurin A subunit beta isoform; Calnb; CAM-PRP catalytic subunit; CNA beta; Cnab; CnAbeta; PP2BA beta; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
Orthologs:
Homo sapiens (human) : PPP3CB (protein phosphatase 3 catalytic subunit beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ppp3cb (protein phosphatase 3 catalytic subunit beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppp3cb (protein phosphatase 3 catalytic subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : PPP3CB (protein phosphatase 3 catalytic subunit beta)
Canis lupus familiaris (dog) : PPP3CB (protein phosphatase 3 catalytic subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppp3cb (protein phosphatase 3 catalytic subunit beta)
Sus scrofa (pig) : PPP3CB (protein phosphatase 3 catalytic subunit beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381420,499,364 - 20,546,573 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371421,318,536 - 21,365,795 (-)NCBIGRCm37mm9NCBIm37
MGSCv361419,288,592 - 19,335,096 (-)NCBImm8
Celera1416,880,736 - 16,928,039 (-)NCBICelera
Cytogenetic Map14 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ppp3cb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11135
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.