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Gene: Rb1 (RB transcriptional corepressor 1) Mus musculus
Symbol: Rb1
Name: RB transcriptional corepressor 1
CRRD ID: 11219
Description: Exhibits RNA polymerase II activating transcription factor binding activity and enzyme binding activity. Involved in several processes, including negative regulation of cell cycle; neuron development; and regulation of transcription, DNA-templated. Localizes to Rb-E2F complex; nucleus; and spindle. Predicted to colocalize with cyclin/CDK positive transcription elongation factor complex. Is expressed in several structures, including alimentary system; central nervous system; hemolymphoid system; retina; and vibrissa. Human ortholog(s) of this gene implicated in nervous system cancer (multiple); osteosarcoma; prostate cancer; small cell carcinoma; and urinary bladder cancer. Orthologous to human RB1 (RB transcriptional corepressor 1); PARTICIPATES IN ceramide signaling pathway; G1/S transition pathway; RNA polymerase III transcription pathway; INTERACTS WITH (S)-colchicine; (S)-nicotine; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: p; p110-RB1; pp105; pRb; R; Rb; Rb-; Rb-1; retinoblastoma 1; retinoblastoma-associated protein
Homo sapiens (human) : RB1 (RB transcriptional corepressor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rb1 (RB transcriptional corepressor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rb1 (RB transcriptional corepressor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RB1 (RB transcriptional corepressor 1)
Canis lupus familiaris (dog) : RB1 (RB transcriptional corepressor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rb1 (RB transcriptional corepressor 1)
Sus scrofa (pig) : RB1 (RB transcriptional corepressor 1)
Chlorocebus sabaeus (African green monkey) : RB1 (RB transcriptional corepressor 1)
Heterocephalus glaber (naked mole-rat) : Rb1 (RB transcriptional corepressor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391473,430,298 - 73,563,446 (-)NCBI
GRCm381473,192,858 - 73,325,951 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1473,183,673 - 73,325,822 (-)EnsemblGRCm38mm10GRCm38
MGSCv371473,595,309 - 73,725,598 (-)NCBIGRCm37mm9NCBIm37
MGSCv361471,929,656 - 72,059,895 (-)NCBImm8
Celera1470,715,843 - 70,870,859 (-)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1438.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data