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Gene: Ccl2 (chemokine (C-C motif) ligand 2) Mus musculus
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Symbol: Ccl2
Name: chemokine (C-C motif) ligand 2
CRRD ID: 11275
Description: Exhibits CCR2 chemokine receptor binding activity and cytokine activity. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of leukocyte chemotaxis; and positive regulation of macromolecule metabolic process. Localizes to extracellular space. Predicted to colocalize with C-fiber. Is expressed in several structures, including heart; nervous system; nucleus pulposus; retina; and vibrissa. Used to study age related macular degeneration. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; aggressive periodontitis; autoimmune disease (multiple); gastrointestinal system cancer (multiple); and tuberculosis (multiple). Orthologous to human CCL2 (C-C motif chemokine ligand 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI323594; C-C motif chemokine 2; HC11; JE; MCA; MCAF; MCP; MCP-; MCP-1; MCP1; monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic protein 1; platelet-derived growth factor-inducible protein JE; Scy; Scya2; Sig; Sigje; small inducible cytokine A2; small-inducible cytokine A2; SMC-C; SMC-CF
Orthologs:
Homo sapiens (human) : CCL2 (C-C motif chemokine ligand 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ccl2 (C-C motif chemokine ligand 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CCL2 (C-C motif chemokine ligand 2)
Canis lupus familiaris (dog) : CCL2 (C-C motif chemokine ligand 2)
Sus scrofa (pig) : CCL2 (chemokine (C-C motif) ligand 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391181,926,403 - 81,928,278 (+)NCBI
GRCm381182,035,577 - 82,037,452 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1182,035,571 - 82,037,453 (+)EnsemblGRCm38mm10GRCm38
MGSCv371181,849,079 - 81,850,954 (+)NCBIGRCm37mm9NCBIm37
MGSCv361181,851,769 - 81,853,422 (+)NCBImm8
Celera1191,649,026 - 91,650,901 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1149.82NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model