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Gene: Cxcl12 (chemokine (C-X-C motif) ligand 12) Mus musculus
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Symbol: Cxcl12
Name: chemokine (C-X-C motif) ligand 12
Description: Exhibits chemokine activity. Involved in several processes, including branching involved in blood vessel morphogenesis; gamete generation; and nervous system development. Localizes to external side of plasma membrane. Human ortholog(s) of this gene implicated in breast carcinoma; diabetic angiopathy; human immunodeficiency virus infectious disease; and type 1 diabetes mellitus. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and sensory organ. Orthologous to human CXCL12 (C-X-C motif chemokine ligand 12).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; AI174028; C-X-C motif chemokine 12; Pbsf; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; Scyb12; Sdf1; Sdf1a; Sdf1b; stromal cell-derived factor 1; thymic lymphoma cell-stimulating factor; Tlsf; Tlsfa; Tlsfb; Tpar1
Orthologs:
Homo sapiens (human) : CXCL12 (C-X-C motif chemokine ligand 12)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cxcl12 (C-X-C motif chemokine ligand 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cxcl12 (C-X-C motif chemokine ligand 12)
Pan paniscus (bonobo/pygmy chimpanzee) : CXCL12 (C-X-C motif chemokine ligand 12)
Canis lupus familiaris (dog) : CXCL12 (C-X-C motif chemokine ligand 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cxcl12 (C-X-C motif chemokine ligand 12)
Sus scrofa (pig) : CXCL12 (C-X-C motif chemokine ligand 12)
Chlorocebus sabaeus (African green monkey) : CXCL12 (C-X-C motif chemokine ligand 12)
Heterocephalus glaber (naked mole-rat) : Cxcl12 (C-X-C motif chemokine ligand 12)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl6117,168,535 - 117,181,367 (+)EnsemblGRCm38mm10GRCm38
GRCm386117,168,535 - 117,181,368 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376117,118,553 - 117,131,386 (+)NCBIGRCm37mm9NCBIm37
MGSCv366117,134,182 - 117,146,986 (+)NCBImm8
Celera6118,991,272 - 119,004,105 (+)NCBICelera
Cytogenetic Map6F1NCBI
cM Map654.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cxcl12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11280
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.