Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cxcl12 (chemokine (C-X-C motif) ligand 12) Mus musculus
Symbol: Cxcl12
Name: chemokine (C-X-C motif) ligand 12
Description: Exhibits chemokine activity. Involved in several processes, including branching involved in blood vessel morphogenesis; gamete generation; and nervous system development. Localizes to external side of plasma membrane. Human ortholog(s) of this gene implicated in breast carcinoma; diabetic angiopathy; human immunodeficiency virus infectious disease; and type 1 diabetes mellitus. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and sensory organ. Orthologous to human CXCL12 (C-X-C motif chemokine ligand 12).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; AI174028; C-X-C motif chemokine 12; Pbsf; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; Scyb12; Sdf1; Sdf1a; Sdf1b; stromal cell-derived factor 1; thymic lymphoma cell-stimulating factor; Tlsf; Tlsfa; Tlsfb; Tpar1
Homo sapiens (human) : CXCL12 (C-X-C motif chemokine ligand 12)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cxcl12 (C-X-C motif chemokine ligand 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cxcl12 (C-X-C motif chemokine ligand 12)
Pan paniscus (bonobo/pygmy chimpanzee) : CXCL12 (C-X-C motif chemokine ligand 12)
Canis lupus familiaris (dog) : CXCL12 (C-X-C motif chemokine ligand 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cxcl12 (C-X-C motif chemokine ligand 12)
Sus scrofa (pig) : CXCL12 (C-X-C motif chemokine ligand 12)
Chlorocebus sabaeus (African green monkey) : CXCL12 (C-X-C motif chemokine ligand 12)
Heterocephalus glaber (naked mole-rat) : Cxcl12 (C-X-C motif chemokine ligand 12)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl6117,168,535 - 117,181,367 (+)EnsemblGRCm38mm10GRCm38
GRCm386117,168,535 - 117,181,368 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376117,118,553 - 117,131,386 (+)NCBIGRCm37mm9NCBIm37
MGSCv366117,134,182 - 117,146,986 (+)NCBImm8
Celera6118,991,272 - 119,004,105 (+)NCBICelera
Cytogenetic Map6F1NCBI
cM Map654.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cxcl12
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11280
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.