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Gene: Sele (selectin, endothelial cell) Mus musculus
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Symbol: Sele
Name: selectin, endothelial cell
Description: Predicted to have several functions, including oligosaccharide binding activity; phospholipase binding activity; and sialic acid binding activity. Involved in positive regulation of leukocyte migration. Predicted to localize to several cellular components, including the caveola; clathrin-coated pit; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; brain ischemia; cerebrovascular disease; and coronary artery disease. Is expressed in several structures, including adrenal gland; genitourinary system; incisor; integumental system; and limb segment. Orthologous to human SELE (selectin E); PARTICIPATES IN eicosanoid signaling pathway; malaria pathway; sleeping sickness pathway; INTERACTS WITH (R)-linalyl acetate; 3,3',4,4',5-pentachlorobiphenyl; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD62 antigen-like family member E; CD62E; E-selectin; Elam; ELAM-1; endothelial leukocyte adhesion molecule 1; LECAM2; leukocyte-endothelial cell adhesion molecule 2
Orthologs:
Homo sapiens (human) : SELE (selectin E)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sele (selectin E)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sele (selectin E)
Pan paniscus (bonobo/pygmy chimpanzee) : SELE (selectin E)
Canis lupus familiaris (dog) : SELE (selectin E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sele (selectin E)
Sus scrofa (pig) : SELE (selectin E)
Chlorocebus sabaeus (African green monkey) : SELE (selectin E)
Heterocephalus glaber (naked mole-rat) : Sele (selectin E)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1164,048,234 - 164,057,677 (+)EnsemblGRCm38mm10GRCm38
GRCm381164,039,614 - 164,058,487 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371165,978,365 - 165,987,808 (+)NCBIGRCm37mm9NCBIm37
MGSCv361165,884,909 - 165,894,352 (+)NCBImm8
Celera1166,489,844 - 166,499,312 (+)NCBICelera
Cytogenetic Map1H2.2NCBI
cM Map171.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sele
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11283
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.