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Gene: Sele (selectin, endothelial cell) Mus musculus
Symbol: Sele
Name: selectin, endothelial cell
Description: Predicted to have several functions, including oligosaccharide binding activity; phospholipase binding activity; and sialic acid binding activity. Involved in positive regulation of leukocyte migration. Predicted to localize to several cellular components, including the caveola; clathrin-coated pit; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; brain ischemia; cerebrovascular disease; and coronary artery disease. Is expressed in several structures, including adrenal gland; genitourinary system; incisor; integumental system; and limb segment. Orthologous to human SELE (selectin E); PARTICIPATES IN eicosanoid signaling pathway; malaria pathway; sleeping sickness pathway; INTERACTS WITH (R)-linalyl acetate; 3,3',4,4',5-pentachlorobiphenyl; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD62 antigen-like family member E; CD62E; E-selectin; Elam; ELAM-1; endothelial leukocyte adhesion molecule 1; LECAM2; leukocyte-endothelial cell adhesion molecule 2
Homo sapiens (human) : SELE (selectin E)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sele (selectin E)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sele (selectin E)
Pan paniscus (bonobo/pygmy chimpanzee) : SELE (selectin E)
Canis lupus familiaris (dog) : SELE (selectin E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sele (selectin E)
Sus scrofa (pig) : SELE (selectin E)
Chlorocebus sabaeus (African green monkey) : SELE (selectin E)
Heterocephalus glaber (naked mole-rat) : Sele (selectin E)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1164,048,234 - 164,057,677 (+)EnsemblGRCm38mm10GRCm38
GRCm381164,039,614 - 164,058,487 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371165,978,365 - 165,987,808 (+)NCBIGRCm37mm9NCBIm37
MGSCv361165,884,909 - 165,894,352 (+)NCBImm8
Celera1166,489,844 - 166,499,312 (+)NCBICelera
Cytogenetic Map1H2.2NCBI
cM Map171.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sele
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11283
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.