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Gene: Ighm (immunoglobulin heavy constant mu) Mus musculus
Symbol: Ighm
Name: immunoglobulin heavy constant mu
Description: Exhibits several functions, including antigen binding activity; identical protein binding activity; and immunoglobulin receptor binding activity. Involved in several processes, including early endosome to late endosome transport; immunoglobulin mediated immune response; and positive regulation of protein phosphorylation. Localizes to several cellular components, including the B cell receptor complex; external side of plasma membrane; and immunoglobulin complex, circulating. Used to study non-Hodgkin lymphoma and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in agammaglobulinemia. Is expressed in several structures, including brain; hemolymphoid system; and liver. Orthologous to human IGHM (immunoglobulin heavy constant mu); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-methylcholanthrene; 4-hydroxyphenyl retinamide.
Type: gene
RefSeq Status: VALIDATED
Also known as: AI326478; Igh-6; Igh-M; Igh6; Igm; muH
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl12113,418,558 - 113,422,730 (-)Ensembl
GRCm3812113,418,826 - 113,422,730 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712114,657,037 - 114,660,941 (-)NCBIGRCm37mm9NCBIm37
Celera12114,605,174 - 114,863,569 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1262.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ighm
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11303086
Created: 2016-06-28
Species: Mus musculus
Last Modified: 2020-02-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.