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Gene: Slc4a1 (solute carrier family 4 (anion exchanger), member 1) Mus musculus
Symbol: Slc4a1
Name: solute carrier family 4 (anion exchanger), member 1
Description: Exhibits anion transmembrane transporter activity; ankyrin binding activity; and hemoglobin binding activity. Involved in several processes, including anion transport; erythrocyte development; and negative regulation of glycolytic process through fructose-6-phosphate. Localizes to basolateral plasma membrane; cortical cytoskeleton; and cytoplasmic side of plasma membrane. Is expressed in several structures, including blood; blood vessel; liver; lung; and metanephros. Used to study hereditary spherocytosis type 4 and renal tubular acidosis. Human ortholog(s) of this gene implicated in congenital hemolytic anemia; hereditary spherocytosis; hereditary spherocytosis type 4; malaria; and renal tubular acidosis. Orthologous to human SLC4A1 (solute carrier family 4 member 1 (Diego blood group)); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AE 1; Ae1; anion exchange protein 1; anion exchanger 1; band 3 anion transport protein; CD233; Empb3; erythrocyte membrane protein band 3; l11Jus51; MEB3; solute carrier family 4 member 1
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl11102,348,824 - 102,366,203 (-)EnsemblGRCm38mm10GRCm38
GRCm3811102,348,820 - 102,365,281 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711102,210,134 - 102,226,595 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611102,164,917 - 102,181,205 (-)NCBImm8
Celera11114,058,195 - 114,074,658 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1166.29NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Slc4a1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11309
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.