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Gene: Slc9a1 (solute carrier family 9 (sodium/hydrogen exchanger), member 1) Mus musculus
Symbol: Slc9a1
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 1
Description: Exhibits sodium:proton antiporter activity. Involved in several processes, including cardiac muscle cell differentiation; regulation of pH; and response to acidic pH. Localizes to apical plasma membrane. Is expressed in several structures, including alimentary system; early conceptus; nervous system; oocyte; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 19 and congestive heart failure. Orthologous to human SLC9A1 (solute carrier family 9 member A1); PARTICIPATES IN endothelin signaling pathway; bile acid transport pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Apnh; AW554487; mir-5122; Mir5122; Na(+)/H(+) exchanger 1; Na+/H+ antiporter; Na+/H+, amiloride sensitive; NHE-1; Nhe1; slow-wave epilepsy; sodium/hydrogen exchanger 1; solute carrier family 9 member 1; solute carrier family 9, member 1; swe
Homo sapiens (human) : SLC9A1 (solute carrier family 9 member A1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc9a1 (solute carrier family 9 member A1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc9a1 (solute carrier family 9 member A1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC9A1 (solute carrier family 9 member A1)
Canis lupus familiaris (dog) : SLC9A1 (solute carrier family 9 member A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc9a1 (solute carrier family 9 member A1)
Sus scrofa (pig) : SLC9A1 (solute carrier family 9 member A1)
Chlorocebus sabaeus (African green monkey) : SLC9A1 (solute carrier family 9 member A1)
Heterocephalus glaber (naked mole-rat) : Slc9a1 (solute carrier family 9 member A1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl4133,369,706 - 133,423,702 (+)EnsemblGRCm38mm10GRCm38
GRCm384133,369,711 - 133,423,702 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374132,925,687 - 132,979,613 (+)NCBIGRCm37mm9NCBIm37
MGSCv364132,642,305 - 132,695,773 (+)NCBImm8
Celera4131,535,491 - 131,589,316 (+)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map466.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Slc9a1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11317
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.