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Gene: Snai2 (snail family zinc finger 2) Mus musculus
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Symbol: Snai2
Name: snail family zinc finger 2
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and chromatin binding activity. Involved in several processes, including desmosome disassembly; endocardial cushion formation; and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Localizes to the cytoplasm and nucleus. Used to study Waardenburg syndrome type 2D. Human ortholog(s) of this gene implicated in Waardenburg syndrome type 2D and piebaldism. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and limb. Orthologous to human SNAI2 (snail family transcriptional repressor 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-ethylhexan-1-ol; 2-Ethylhexanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: neural crest transcription factor Slug; Slug; slug, chicken homolog; Slugh; snail homolog 2; Snail2; zinc finger protein SNAI2
Orthologs:
Homo sapiens (human) : SNAI2 (snail family transcriptional repressor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Snai2 (snail family transcriptional repressor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snai2 (snail family transcriptional repressor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SNAI2 (snail family transcriptional repressor 2)
Canis lupus familiaris (dog) : SNAI2 (snail family transcriptional repressor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snai2 (snail family transcriptional repressor 2)
Sus scrofa (pig) : SNAI2 (snail family transcriptional repressor 2)
Chlorocebus sabaeus (African green monkey) : SNAI2 (snail family transcriptional repressor 2)
Heterocephalus glaber (naked mole-rat) : Snai2 (snail family transcriptional repressor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1614,705,852 - 14,709,385 (+)Ensembl
GRCm381614,705,852 - 14,709,395 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371614,705,952 - 14,709,478 (+)NCBIGRCm37mm9NCBIm37
MGSCv361614,619,437 - 14,622,963 (+)NCBImm8
Celera1615,292,698 - 15,296,242 (+)NCBICelera
Cytogenetic Map16 A1NCBI
cM Map1610.07NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Snai2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11321
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.