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Gene: Stat5b (signal transducer and activator of transcription 5B) Mus musculus
Symbol: Stat5b
Name: signal transducer and activator of transcription 5B
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Involved in several processes, including animal organ development; cell surface receptor signaling pathway; and positive regulation of lymphocyte activation. Localizes to cytoplasm and nucleus. Is expressed in several structures, including adipose tissue; alimentary system; brain; genitourinary system; and immune system. Orthologous to human STAT5B (signal transducer and activator of transcription 5B); PARTICIPATES IN erythropoietin signaling pathway; fibroblast growth factor signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; INTERACTS WITH 1-benzofuran; 1-tert-Butoxy-2-propanol; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: mammary gland factor STAT5B
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl11100,780,731 - 100,850,724 (-)EnsemblGRCm38mm10GRCm38
GRCm3811100,780,731 - 100,859,004 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711100,642,045 - 100,711,899 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611101,557,264 - 101,599,060 (-)NCBImm8
MGSCv3611100,596,821 - 100,638,618 (-)NCBImm8
Cytogenetic Map11DNCBI
cM Map1163.63NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Stat5b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11352
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.