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Gene: Hnf1a (HNF1 homeobox A) Mus musculus
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Symbol: Hnf1a
Name: HNF1 homeobox A
Description: Exhibits several functions, including DNA-binding transcription factor activity; identical protein binding activity; and protein dimerization activity. Involved in several processes, including animal organ development; glucose transmembrane transport; and lipid transport. Localizes to several cellular components, including photoreceptor outer segment; pronucleus; and transcription regulator complex. Is expressed in several structures, including extraembryonic component; genitourinary system; gut; septum transversum hepatic component; and spleen. Used to study maturity-onset diabetes of the young type 3; phenylketonuria; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in glucose metabolism disease (multiple); liver disease (multiple); and renal cell carcinoma. Orthologous to human HNF1A (HNF1 homeobox A).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI323641; hepatocyte nuclear factor 1; hepatocyte nuclear factor 1-alpha; Hnf-1; HNF-1-alpha; HNF-1A; HNF1; HNF1-alpha; HNF1[a]; Hnf1alpha; LFB1; liver-specific transcription factor LF-B1; Tcf-1; Tcf1; transcription factor 1
Orthologs:
Homo sapiens (human) : HNF1A (HNF1 homeobox A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hnf1a (HNF1 homeobox A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hnf1a (HNF1 homeobox A)
Pan paniscus (bonobo/pygmy chimpanzee) : HNF1A (HNF1 homeobox A)
Canis lupus familiaris (dog) : HNF1A (HNF1 homeobox A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hnf1a (HNF1 homeobox A)
Sus scrofa (pig) : HNF1A (HNF1 homeobox A)
Chlorocebus sabaeus (African green monkey) : HNF1A (HNF1 homeobox A)
Heterocephalus glaber (naked mole-rat) : Hnf1a (HNF1 homeobox A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl5114,948,980 - 114,971,094 (-)EnsemblGRCm38mm10GRCm38
GRCm385114,948,980 - 114,971,062 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375115,398,989 - 115,421,071 (-)NCBIGRCm37mm9NCBIm37
MGSCv365115,209,360 - 115,232,037 (-)NCBImm8
Celera5112,043,825 - 112,067,328 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hnf1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11397
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.