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Gene: Gstm3 (glutathione S-transferase mu 3) Rattus norvegicus
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Symbol: Gstm3
Name: glutathione S-transferase mu 3
Description: Exhibits glutathione transferase activity and protein homodimerization activity. Predicted to be involved in several processes, including cellular detoxification of nitrogen compound; glutathione metabolic process; and nitrobenzene metabolic process. Predicted to localize to the cytosol and intercellular bridge. Human ortholog(s) of this gene implicated in several diseases, including asthma; cystic fibrosis; larynx cancer; neurodegenerative disease (multiple); and osteosarcoma. Orthologous to human GSTM3 (glutathione S-transferase mu 3); PARTICIPATES IN glutathione conjugation pathway; glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH 1-chloro-2,4-dinitrobenzene (ortholog); 17beta-estradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: NEWGENE_620381
Orthologs:
Homo sapiens (human) : GSTM3 (glutathione S-transferase mu 3)  HGNC  Alliance
Mus musculus (house mouse) : Gstm3 (glutathione S-transferase, mu 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gstm3 (glutathione S-transferase mu 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GSTM3 (glutathione S-transferase mu 3)
Canis lupus familiaris (dog) : LOC479911 (glutathione S-transferase Mu 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gstm3 (glutathione S-transferase mu 3)
Sus scrofa (pig) : GSTM3 (glutathione S-transferase mu 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02210,685,204 - 210,688,273 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Celera2188,177,950 - 188,181,024 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Additional Information

External Database Links
Nomenclature History
 
More on Gstm3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11402080
Created: 2016-08-02
Species: Rattus norvegicus
Last Modified: 2019-05-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.