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Gene: Tgfa (transforming growth factor alpha) Mus musculus
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Symbol: Tgfa
Name: transforming growth factor alpha
Description: Predicted to have epidermal growth factor receptor binding activity and growth factor activity. Involved in several processes, including angiogenesis; gland development; and positive regulation of peptidyl-tyrosine phosphorylation. Predicted to colocalize with plasma membrane. Human ortholog(s) of this gene implicated in gastroenteritis and pancreatic cancer. Is expressed in several structures, including alimentary system; brain; cranium; genitourinary system; and sensory organ. Orthologous to human TGFA (transforming growth factor alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: protransforming growth factor alpha; transforming growth factor-alpha; wa-1; wa1; waved 1
Orthologs:
Homo sapiens (human) : TGFA (transforming growth factor alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tgfa (transforming growth factor alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgfa (transforming growth factor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : TGFA (transforming growth factor alpha)
Canis lupus familiaris (dog) : TGFA (transforming growth factor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgfa (transforming growth factor alpha)
Sus scrofa (pig) : TGFA (transforming growth factor alpha)
Chlorocebus sabaeus (African green monkey) : TGFA (transforming growth factor alpha)
Heterocephalus glaber (naked mole-rat) : Tgfa (transforming growth factor alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl686,195,223 - 86,275,719 (+)EnsemblGRCm38mm10GRCm38
GRCm38686,195,038 - 86,275,743 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37686,145,245 - 86,225,443 (+)NCBIGRCm37mm9NCBIm37
MGSCv36686,161,050 - 86,240,791 (+)NCBImm8
Celera688,129,264 - 88,209,219 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map637.62NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tgfa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11411
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.