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Gene: Tgfa (transforming growth factor alpha) Mus musculus
Symbol: Tgfa
Name: transforming growth factor alpha
Description: Predicted to have epidermal growth factor receptor binding activity and growth factor activity. Involved in several processes, including angiogenesis; gland development; and positive regulation of peptidyl-tyrosine phosphorylation. Predicted to colocalize with plasma membrane. Human ortholog(s) of this gene implicated in gastroenteritis and pancreatic cancer. Is expressed in several structures, including alimentary system; brain; cranium; genitourinary system; and sensory organ. Orthologous to human TGFA (transforming growth factor alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: protransforming growth factor alpha; transforming growth factor-alpha; wa-1; wa1; waved 1
Homo sapiens (human) : TGFA (transforming growth factor alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tgfa (transforming growth factor alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgfa (transforming growth factor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : TGFA (transforming growth factor alpha)
Canis lupus familiaris (dog) : TGFA (transforming growth factor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgfa (transforming growth factor alpha)
Sus scrofa (pig) : TGFA (transforming growth factor alpha)
Chlorocebus sabaeus (African green monkey) : TGFA (transforming growth factor alpha)
Heterocephalus glaber (naked mole-rat) : Tgfa (transforming growth factor alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl686,195,223 - 86,275,719 (+)EnsemblGRCm38mm10GRCm38
GRCm38686,195,038 - 86,275,743 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37686,145,245 - 86,225,443 (+)NCBIGRCm37mm9NCBIm37
MGSCv36686,161,050 - 86,240,791 (+)NCBImm8
Celera688,129,264 - 88,209,219 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map637.62NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tgfa
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11411
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.