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Gene: Tnnt3 (troponin T3, skeletal, fast) Mus musculus
Symbol: Tnnt3
Name: troponin T3, skeletal, fast
Description: Predicted to contribute to actin binding activity; calcium-dependent ATPase activity; and tropomyosin binding activity. Predicted to be involved in several processes, including regulation of ATPase activity; sarcomere organization; and striated muscle contraction. Predicted to localize to troponin complex. Human ortholog(s) of this gene implicated in distal arthrogryposis type 2B and distal arthrogryposis type 2B2. Is expressed in several structures, including diaphragm; eyelid epithelium; lower jaw; musculature; and urinary system. Orthologous to human TNNT3 (troponin T3, fast skeletal type); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: fast skeletal muscle troponin T; fast skeletal muscle troponin T3; fTnT; skeletal muscle fast-twitch TnT; tnTf; troponin T, fast skeletal muscle
Homo sapiens (human) : TNNT3 (troponin T3, fast skeletal type)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tnnt3 (troponin T3, fast skeletal type)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnnt3 (troponin T3, fast skeletal type)
Pan paniscus (bonobo/pygmy chimpanzee) : TNNT3 (troponin T3, fast skeletal type)
Canis lupus familiaris (dog) : TNNT3 (troponin T3, fast skeletal type)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnnt3 (troponin T3, fast skeletal type)
Sus scrofa (pig) : TNNT3 (troponin T3, fast skeletal type)
Chlorocebus sabaeus (African green monkey) : TNNT3 (troponin T3, fast skeletal type)
Heterocephalus glaber (naked mole-rat) : Tnnt3 (troponin T3, fast skeletal type)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl7142,498,836 - 142,516,009 (+)EnsemblGRCm38mm10GRCm38
GRCm387142,498,771 - 142,516,213 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377149,684,741 - 149,701,914 (+)NCBIGRCm37mm9NCBIm37
MGSCv367142,308,233 - 142,325,393 (+)NCBImm8
Celera7142,254,685 - 142,271,858 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map787.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tnnt3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11436
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-04-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.