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Gene: Tyro3 (TYRO3 protein tyrosine kinase 3) Mus musculus
Symbol: Tyro3
Name: TYRO3 protein tyrosine kinase 3
CRRD ID: 11467
Description: Predicted to have phosphatidylinositol 3-kinase binding activity and transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including animal organ development; negative regulation of defense response; and platelet aggregation. Predicted to localize to several cellular components, including cell surface; endoplasmic reticulum membrane; and nuclear envelope. Is expressed in several structures, including brain; genitourinary system; gut; limb; and sensory organ. Orthologous to human TYRO3 (TYRO3 protein tyrosine kinase); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI323366; Br; Brt; Dtk; Etk-2; etk2/tyro3; R; receptor tyrosine kinase; Rse; Sk; Sky; Ti; Tif; tk19-1; TK19-2; tyrosine kinase growth factor receptor; tyrosine kinase growth factor receptor isoform III; tyrosine-protein kinase DTK; tyrosine-protein kinase receptor TYRO3; tyrosine-protein kinase RSE; tyrosine-protein kinase TIF
Homo sapiens (human) : TYRO3 (TYRO3 protein tyrosine kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tyro3 (TYRO3 protein tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tyro3 (TYRO3 protein tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : TYRO3 (TYRO3 protein tyrosine kinase)
Canis lupus familiaris (dog) : TYRO3 (TYRO3 protein tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tyro3 (TYRO3 protein tyrosine kinase)
Sus scrofa (pig) : TYRO3 (TYRO3 protein tyrosine kinase)
Chlorocebus sabaeus (African green monkey) : TYRO3 (TYRO3 protein tyrosine kinase)
Heterocephalus glaber (naked mole-rat) : Tyro3 (TYRO3 protein tyrosine kinase)
more info ...
Related Pseudogenes: Tyro3-rs1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm392119,628,221 - 119,648,585 (+)NCBI
GRCm382119,797,740 - 119,818,104 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2119,797,733 - 119,818,104 (+)EnsemblGRCm38mm10GRCm38
MGSCv372119,625,250 - 119,643,840 (+)NCBIGRCm37mm9NCBIm37
MGSCv362119,490,955 - 119,509,545 (+)NCBImm8
Celera2120,956,991 - 120,973,578 (+)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tyro3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11467
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.