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Gene: Tyro3 (TYRO3 protein tyrosine kinase 3) Mus musculus
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Symbol: Tyro3
Name: TYRO3 protein tyrosine kinase 3
CRRD ID: 11467
Description: Predicted to have phosphatidylinositol 3-kinase binding activity and transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including animal organ development; negative regulation of defense response; and platelet aggregation. Predicted to localize to several cellular components, including cell surface; endoplasmic reticulum membrane; and nuclear envelope. Is expressed in several structures, including brain; genitourinary system; gut; limb; and sensory organ. Orthologous to human TYRO3 (TYRO3 protein tyrosine kinase); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI323366; Br; Brt; Dtk; Etk-2; etk2/tyro3; R; receptor tyrosine kinase; Rse; Sk; Sky; Ti; Tif; tk19-1; TK19-2; tyrosine kinase growth factor receptor; tyrosine kinase growth factor receptor isoform III; tyrosine-protein kinase DTK; tyrosine-protein kinase receptor TYRO3; tyrosine-protein kinase RSE; tyrosine-protein kinase TIF
Orthologs:
Homo sapiens (human) : TYRO3 (TYRO3 protein tyrosine kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tyro3 (TYRO3 protein tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tyro3 (TYRO3 protein tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : TYRO3 (TYRO3 protein tyrosine kinase)
Canis lupus familiaris (dog) : TYRO3 (TYRO3 protein tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tyro3 (TYRO3 protein tyrosine kinase)
Sus scrofa (pig) : TYRO3 (TYRO3 protein tyrosine kinase)
Chlorocebus sabaeus (African green monkey) : TYRO3 (TYRO3 protein tyrosine kinase)
Heterocephalus glaber (naked mole-rat) : Tyro3 (TYRO3 protein tyrosine kinase)
more info ...
Related Pseudogenes: Tyro3-rs1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392119,628,221 - 119,648,585 (+)NCBI
GRCm382119,797,740 - 119,818,104 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2119,797,733 - 119,818,104 (+)EnsemblGRCm38mm10GRCm38
MGSCv372119,625,250 - 119,643,840 (+)NCBIGRCm37mm9NCBIm37
MGSCv362119,490,955 - 119,509,545 (+)NCBImm8
Celera2120,956,991 - 120,973,578 (+)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tyro3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11467
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.