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Gene: Vdr (vitamin D (1,25-dihydroxyvitamin D3) receptor) Mus musculus
Symbol: Vdr
Name: vitamin D (1,25-dihydroxyvitamin D3) receptor
Description: Exhibits DNA binding activity and nuclear receptor activity. Predicted to contribute to DNA-binding transcription factor activity and vitamin D response element binding activity. Involved in several processes, including mammary gland development; positive regulation of apoptotic process involved in mammary gland involution; and regulation of cellular biosynthetic process. Predicted to colocalize with caveola. Used to study osteoporosis and rickets. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hypersensitivity disease (multiple); carcinoma (multiple); liver disease (multiple); melanoma (multiple); and tuberculosis (multiple). Is expressed in several structures, including alimentary system; metanephros; nervous system; sensory organ; and skeleton. Orthologous to human VDR (vitamin D receptor); PARTICIPATES IN altered p53 signaling pathway; tuberculosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 24,25-Dihydroxyvitamin D; 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1,25-dihydroxyvitamin D3 receptor; Nr1i1; nuclear receptor subfamily 1 group I member 1; vitamin D receptor; vitamin D3 receptor
Homo sapiens (human) : VDR (vitamin D receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Vdr (vitamin D receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vdr (vitamin D receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : VDR (vitamin D receptor)
Canis lupus familiaris (dog) : VDR (vitamin D receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vdr (vitamin D receptor)
Sus scrofa (pig) : VDR (vitamin D receptor)
Chlorocebus sabaeus (African green monkey) : VDR (vitamin D receptor)
Heterocephalus glaber (naked mole-rat) : Vdr (vitamin D receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1597,854,425 - 97,910,630 (-)EnsemblGRCm38mm10GRCm38
GRCm381597,854,427 - 97,908,296 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371597,684,858 - 97,738,727 (-)NCBIGRCm37mm9NCBIm37
MGSCv361597,682,461 - 97,736,330 (-)NCBImm8
Celera1599,981,938 - 100,035,599 (-)NCBICelera
Cytogenetic Map15F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Vdr
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11484
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.